STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mltFPutative transglycosylase; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (481 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
     
 0.690
rseB
sigma-E factor regulatory protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri sigma-E factor regulatory protein RseB precursor RseB or b2571 or z3853 or ecs3437 or sf2633 SWALL:RSEB_ECOLI (SWALL:P46186) (318 aa) fasta scores: E(): 3.1e-69, 57.36% id in 319 aa.
  
     0.546
lolB
Outer-membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
 
     0.480
hemY
Porphyrin biosynthetic protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri HemY protein HemY or b3802 or c4721 or z5316 or ecs4732 or sf3874 SWALL:HEMY_ECOLI (SWALL:P09128) (398 aa) fasta scores: E(): 1.3e-109, 73.02% id in 393 aa, and to Salmonella typhi porphyrin biosynthetic protein sty3624 SWALL:Q8Z398 (EMBL:AL627279) (399 aa) fasta scores: E(): 7e-108, 71.24% id in 393 aa.
  
   
 0.463
nudJ
Putative MutT family protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri putative nudix hydrolase ymfb or b1134 or c1513 or z1863 or ecs1606 or sf1153 SWALL:YMFB_ECOLI (SWALL:P75965) (153 aa) fasta scores: E(): 2.6e-48, 75.67% id in 148 aa, and to Yersinia pestis hypothetical protein ypo1639 or y1800 SWALL:AAM85368 (EMBL:AJ414149) (148 aa) fasta scores: E(): 8.6e-46, 71.62% id in 148 aa.
  
     0.452
mltD
Similar to Escherichia coli, and Escherichia coli O6 membrane-bound lytic murein transglycosylase D precursor MltD or DniR or b0211 or c0248 SWALL:MLTD_ECOLI (SWALL:P23931) (452 aa) fasta scores: E(): 7e-113, 66.81% id in 464 aa.
 
   
 0.428
hemX
Similar to Escherichia coli putative uroporphyrin-III C-methyltransferase HemX or b3803 SWALL:HEMX_ECOLI (SWALL:P09127) (393 aa) fasta scores: E(): 5.1e-71, 60.54% id in 370 aa.
  
     0.419
ECA3341
Similar to Yersinia pestis hypothetical protein ypo1080 or y3096 SWALL:AAM86646 (EMBL:AJ414146) (239 aa) fasta scores: E(): 6.6e-62, 61.86% id in 236 aa, and to Salmonella typhimurium putative sam-dependent methyltransferase yafs or stm0262 SWALL:Q8ZRM1 (EMBL:AE008707) (240 aa) fasta scores: E(): 6.6e-60, 59.07% id in 237 aa.
  
     0.418
plsB
Glycerol-3-phosphate acyltransferase; Similar to Escherichia coli, and Escherichia coli O6 glycerol-3-phosphate acyltransferase PlsB or b4041 or c5011 SWALL:PLSB_ECOLI (SWALL:P00482) (806 aa) fasta scores: E(): 0, 77.08% id in 803 aa; Belongs to the GPAT/DAPAT family.
  
     0.414
ftsL
Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
     0.410
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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