STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tadAPutative cytidine and deoxycytidylate deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (174 aa)    
Predicted Functional Partners:
birA
Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
 
    0.941
hisI
Similar to Escherichia coli histidine biosynthesis bifunctional protein HisIE [includes: phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase HisI or hisie or b2026 SWALL:HIS2_ECOLI (SWALL:P06989) (203 aa) fasta scores: E(): 2e-64, 80.09% id in 201 aa; In the N-terminal section; belongs to the PRA-CH family.
   
  
 0.936
xthA
Similar to Escherichia coli exodeoxyribonuclease III XthA or Xth or b1749 SWALL:EX3_ECOLI (SWALL:P09030) (268 aa) fasta scores: E(): 1.3e-87, 76.31% id in 266 aa.
   
 
 0.724
garK
Glycerate kinase 2; Similar to Escherichia coli glycerate kinase 2 GarK or b3124 SWALL:GRK2_ECOLI (SWALL:P23524) (381 aa) fasta scores: E(): 6.4e-89, 70.5% id in 373 aa, and to Bacillus subtilis glycerate kinase GalxK or s14A SWALL:GRK_BACSU (SWALL:P42100) (382 aa) fasta scores: E(): 3.9e-78, 58.57% id in 379 aa; Belongs to the glycerate kinase type-1 family.
 
 
    0.682
ECA3261
Similar to Yersinia pestis putative membrane protein ypo2924 SWALL:Q8ZCP9 (EMBL:AJ414154) (215 aa) fasta scores: E(): 1.7e-62, 74.27% id in 206 aa, and to Salmonella typhimurium putatative phosphoserine phosphatase yfhb or stm2569 SWALL:Q8ZN27 (EMBL:AE008817) (211 aa) fasta scores: E(): 3e-62, 71.01% id in 207 aa.
     
 0.661
ECA2374
Similar to Yersinia pestis hypothetical protein Ypo2072 SWALL:Q8ZET1 (EMBL:AJ414151) (232 aa) fasta scores: E(): 1.3e-62, 72.84% id in 232 aa, and to Escherichia coli hypothetical protease yeaz yeaz or b1807 SWALL:YEAZ_ECOLI (SWALL:P76256) (231 aa) fasta scores: E(): 2.8e-59, 69.13% id in 230 aa.
 
  
 0.651
adhC
Similar to Escherichia coli alcohol dehydrogenase class III AdhC or b0356 SWALL:ADH3_ECOLI (SWALL:P25437) (369 aa) fasta scores: E(): 1.7e-102, 70.46% id in 369 aa, and to Yersinia pestis alcohol dehydrogenase class III, formaldehyde dehydrogenase adhc or y2667 SWALL:AAM86220 (EMBL:AE013869) (379 aa) fasta scores: E(): 2.3e-130, 91.93% id in 372 aa; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
    0.591
phoH
Phosphate starvation-inducible protein; Similar to Escherichia coli, and Escherichia coli O157:H7 phoh protein PhoH or PsiH or b1020 or z1522 or ecs1266 SWALL:PHOH_ECOLI (SWALL:P31544) (354 aa) fasta scores: E(): 1.1e-85, 86.97% id in 261 aa.
  
     0.590
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
  
 0.587
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
 
  
 0.586
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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