STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aggAAgglutination protein; Similar to Pseudomonas putida agglutination protein precursor AggA SWALL:Q52018 (EMBL:M64540) (452 aa) fasta scores: E(): 4e-73, 47.27% id in 440 aa, and to Vibrio cholerae agglutination protein vc1621 SWALL:Q9KRL6 (EMBL:AE004240) (445 aa) fasta scores: E(): 1.6e-51, 36.58% id in 421 aa. (450 aa)    
Predicted Functional Partners:
ECA3268
Putative toxin secretion ATP-binding protein; Similar to Actinobacillus pleuropneumoniae Rtx-I toxin determinant B Apxib or clyib or hlyib or appB SWALL:RT1B_ACTPL (SWALL:P26760) (707 aa) fasta scores: E(): 1.1e-55, 28.05% id in 695 aa, and to Pseudomonas putida toxin secretion ATP-binding protein pp0167 SWALL:AAN65800 (EMBL:AE016774) (718 aa) fasta scores: E(): 1.1e-188, 69.83% id in 706 aa, and to Pasteurella haemolytica leukotoxin secretion ATP-binding protein lktB SWALL:HLYB_PASHA (SWALL:P16532) (708 aa) fasta scores: E(): 1.1e-55, 27.84% id in 686 aa.
 
  
 0.925
ECA3269
HlyD family secretion protein; Similar to Rhizobium leguminosarum PrsE protein prsE SWALL:O05694 (EMBL:Y12758) (435 aa) fasta scores: E(): 4.6e-27, 29.72% id in 434 aa, and to Pseudomonas putida HlyD family secretion protein pp0166 SWALL:AAN65799 (EMBL:AE016774) (458 aa) fasta scores: E(): 1.9e-103, 65.19% id in 454 aa.
 
   
 0.896
ECA1096
Similar to Pseudomonas putida protein secretion ABC efflux system, membrane fusion protein pp0803 SWALL:AAN66428 (EMBL:AE016777) (394 aa) fasta scores: E(): 9.1e-67, 54.23% id in 378 aa, and to Escherichia coli O157:H7 putative membrane spanning export protein z0635 or ecs0544 SWALL:Q8XD11 (EMBL:AE005229) (391 aa) fasta scores: E(): 2.9e-66, 54.3% id in 372 aa.
 
 
 0.878
hasE
HlyD family secretion protein; Similar to Pseudomonas fluorescens membrane fusion protein HasE SWALL:Q9RHT1 (EMBL:AB023289) (443 aa) fasta scores: E(): 2.5e-67, 52.28% id in 438 aa, and to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 3.8e-62, 46.03% id in 441 aa. Also similar to ECA2782 (47.529% identity in 425 aa overlap).
 
 
 0.840
prtE
Similar to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 9.7e-110, 72.33% id in 441 aa. Also similar to ECA1535 (47.529% in 425 aa overlap.
 
 
 0.839
ECA3265
Hypothetical protein; No significant database matches.
 
     0.832
ECA3263
Putative exported protein; Similar to Pseudomonas putida conserved hypothetical protein pp0164 SWALL:AAN65797 (EMBL:AE016774) (213 aa) fasta scores: E(): 5.6e-51, 59.9% id in 207 aa, and to Vibrio vulnificus predicted periplasmic protein vv21126 SWALL:AAO08027 (EMBL:AE016812) (237 aa) fasta scores: E(): 2e-31, 44.87% id in 205 aa.
 
   
 0.807
ECA1097
Similar to Pseudomonas putida protein secretion ABC efflux system, permease and ATP-binding protein pp0804 SWALL:AAN66429 (EMBL:AE016777) (722 aa) fasta scores: E(): 5.9e-111, 46.31% id in 691 aa, and to Salmonella typhi putative type i secretion protein, ATP-binding protein sty2877 SWALL:Q8Z4H9 (EMBL:AL627276) (718 aa) fasta scores: E(): 1.4e-103, 42.34% id in 692 aa.
 
  
 0.804
macB
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.754
ECA3264
Putative signaling membrane protein; Similar to Pseudomonas putida GGDEF domain protein pp0165 SWALL:AAN65798 (EMBL:AE016774) (648 aa) fasta scores: E(): 8e-140, 56.7% id in 649 aa, and to Vibrio vulnificus fog: EAL domain protein vv21127 SWALL:AAO08028 (EMBL:AE016812) (639 aa) fasta scores: E(): 2.7e-33, 26.2% id in 641 aa.
  
     0.751
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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