STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rseCSimilar to Escherichia coli sigma-E factor regulatory protein RseC or b2570 SWALL:RSEC_ECOLI (SWALL:P46187) (159 aa) fasta scores: E(): 1.4e-23, 49.66% id in 149 aa, and to Yersinia enterocolitica RseC protein rseC SWALL:Q8KQC9 (EMBL:AY098586) (153 aa) fasta scores: E(): 7.2e-27, 55.24% id in 143 aa. (150 aa)    
Predicted Functional Partners:
rseA
sigma-E factor negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases [...]
 
  
 0.914
rseB
sigma-E factor regulatory protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri sigma-E factor regulatory protein RseB precursor RseB or b2571 or z3853 or ecs3437 or sf2633 SWALL:RSEB_ECOLI (SWALL:P46186) (318 aa) fasta scores: E(): 3.1e-69, 57.36% id in 319 aa.
 
   
 0.888
rpoE
RNA polymerase sigma-E factor; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri RNA polymerase sigma-E factor RpoE or SigE or b2573 or c3097 or z3855 or ecs3439 or sf2635 SWALL:RPOE_ECOLI (SWALL:P34086) (191 aa) fasta scores: E(): 6.8e-68, 92.14% id in 191 aa; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.657
rnfG
Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
 
   
 0.613
ECA0272
Similar to Yersinia pestis putative exported protein ypo3670 SWALL:Q8ZAW2 (EMBL:AJ414158) (1307 aa) fasta scores: E(): 0, 56.76% id in 1300 aa, and to Escherichia coli O6 hypothetical protein YhdP SWALL:AAN82440 (EMBL:AE016767) (1266 aa) fasta scores: E(): 2e-213, 54.68% id in 1282 aa.
  
     0.580
rnfC
Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
 
   
 0.569
igaA
Similar to Salmonella typhimurium intracellular growth attenuator protein IgaA or stm3495 SWALL:IGAA_SALTY (SWALL:Q9ACP0) (710 aa) fasta scores: E(): 2.3e-132, 50.14% id in 716 aa, and to Proteus mirabilis flagellar operon control protein UmoB SWALL:UMOB_PROMI (SWALL:O86988) (702 aa) fasta scores: E(): 1.8e-100, 40.11% id in 698 aa.
  
     0.552
nlpI
Lipoprotein; May be involved in cell division.
  
     0.506
recC
Exodeoxyribonuclease V gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...]
  
     0.500
rraB
Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.484
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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