STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rseCSimilar to Escherichia coli sigma-E factor regulatory protein RseC or b2570 SWALL:RSEC_ECOLI (SWALL:P46187) (159 aa) fasta scores: E(): 1.4e-23, 49.66% id in 149 aa, and to Yersinia enterocolitica RseC protein rseC SWALL:Q8KQC9 (EMBL:AY098586) (153 aa) fasta scores: E(): 7.2e-27, 55.24% id in 143 aa. (150 aa)    
Predicted Functional Partners:
rseA
sigma-E factor negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases [...]
 
  
 0.949
rseB
sigma-E factor regulatory protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri sigma-E factor regulatory protein RseB precursor RseB or b2571 or z3853 or ecs3437 or sf2633 SWALL:RSEB_ECOLI (SWALL:P46186) (318 aa) fasta scores: E(): 3.1e-69, 57.36% id in 319 aa.
 
   
 0.898
rpoE
RNA polymerase sigma-E factor; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri RNA polymerase sigma-E factor RpoE or SigE or b2573 or c3097 or z3855 or ecs3439 or sf2635 SWALL:RPOE_ECOLI (SWALL:P34086) (191 aa) fasta scores: E(): 6.8e-68, 92.14% id in 191 aa; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.685
rnfG
Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
 
     0.608
ECA0272
Similar to Yersinia pestis putative exported protein ypo3670 SWALL:Q8ZAW2 (EMBL:AJ414158) (1307 aa) fasta scores: E(): 0, 56.76% id in 1300 aa, and to Escherichia coli O6 hypothetical protein YhdP SWALL:AAN82440 (EMBL:AE016767) (1266 aa) fasta scores: E(): 2e-213, 54.68% id in 1282 aa.
  
     0.580
igaA
Similar to Salmonella typhimurium intracellular growth attenuator protein IgaA or stm3495 SWALL:IGAA_SALTY (SWALL:Q9ACP0) (710 aa) fasta scores: E(): 2.3e-132, 50.14% id in 716 aa, and to Proteus mirabilis flagellar operon control protein UmoB SWALL:UMOB_PROMI (SWALL:O86988) (702 aa) fasta scores: E(): 1.8e-100, 40.11% id in 698 aa.
  
     0.552
rnfC
Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
 
   
 0.531
lepA
GTP-binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.514
nlpI
Lipoprotein; May be involved in cell division.
  
     0.506
lepB
Similar to Escherichia coli signal peptidase I LepB or b2568 SWALL:LEP_ECOLI (SWALL:P00803) (324 aa) fasta scores: E(): 4.7e-93, 69.75% id in 324 aa; Belongs to the peptidase S26 family.
       0.502
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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