STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grcAConserved hypothetical protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. (127 aa)    
Predicted Functional Partners:
cutC-2
Putative formate acetyltransferase; Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde. Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
  
 
   0.931
pflB
Similar to Escherichia coli formate acetyltransferase 1 PflB or Pfl or b0903 SWALL:PFLB_ECOLI (SWALL:P09373) (759 aa) fasta scores: E(): 0, 91.3% id in 759 aa.
    
   0.788
cutD
Putative pyruvate formate-lyase activating enzyme; Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).
  
     0.772
adhE
Aldehyde-alcohol dehydrogenase; Similar to Escherichia coli, and Escherichia coli O157:H7 aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase, acetaldehyde dehydrogenase, and pyruvate-formate-lyase deactivase AdhE or Ana or b1241 or z2016 or ecs1741 SWALL:ADHE_ECOLI (SWALL:P17547) (890 aa) fasta scores: E(): 0, 89.1% id in 890 aa; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
   
 0.715
nrdD
Similar to Escherichia coli anaerobic ribonucleoside-triphosphate reductase NrdD or b4238 SWALL:NRDD_ECOLI (SWALL:P28903) (712 aa) fasta scores: E(): 0, 85.97% id in 713 aa.
  
   
 0.680
nrdG
Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
  
   
 0.522
alaE
Putative membrane protein; Exports L-alanine; Belongs to the AlaE exporter family.
   
  
 0.482
rpiA
Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
      
 0.465
rfbI
Similar to Yersinia pestis, and Yersinia pseudotuberculosis CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3-dehydrase reductase AscD or RfbI or ypo3116 or y1067 SWALL:ASCD_YERPE (SWALL:P37911) (328 aa) fasta scores: E(): 2.8e-45, 45.7% id in 326 aa, and to Salmonella typhimurium RfbI protein or stm2093 SWALL:RFBI_SALTY (SWALL:P26395) (330 aa) fasta scores: E(): 1.1e-50, 46.01% id in 326 aa.
    
  0.459
sspA
Stringent starvation protein A; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri stringent starvation protein A SspA or Ssp or Pog or b3229 or c3982 or z4587 or ecs4102 or sf3269 SWALL:SSPA_ECOLI (SWALL:P05838) (211 aa) fasta scores: E(): 6.2e-67, 84.61% id in 208 aa; Belongs to the GST superfamily.
      
 0.458
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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