STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
erpAConserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. (115 aa)    
Predicted Functional Partners:
hscB
Chaperone protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
 
 
 0.649
nfuA
Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 
 0.647
nifU
Nitrogen fixation protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
  
 0.618
icsU
NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
  
 0.618
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
  
 0.617
nifQ
Nitrogen fixation protein; Similar to Pantoea agglomerans NifQ protein NifQ SWALL:Q52074 (EMBL:X99694) (171 aa) fasta scores: E(): 1.7e-37, 59.64% id in 171 aa, and to Klebsiella pneumoniae NifQ protein NifQ SWALL:NIFQ_KLEPN (SWALL:P10392) (167 aa) fasta scores: E(): 1.8e-33, 58.08% id in 167 aa.
  
  
 0.582
sufD
Conserved hypothetical protein; Similar to Escherichia coli SufD protein SufD or b1681 SWALL:SUFD_ECOLI (SWALL:P77689) (423 aa) fasta scores: E(): 1e-99, 61.5% id in 413 aa, and to Erwinia chrysanthemi SufD protein sSufD SWALL:Q9EXP3 (EMBL:AJ301654) (430 aa) fasta scores: E(): 1.6e-114, 69.78% id in 417 aa.
 
 
 0.577
ECA0758
Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family.
 
 
 0.558
ECA1927
Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri protein ydhd or b1654 or c2048 or z2676 or ecs2363 or sf1682 SWALL:YDHD_ECOLI (SWALL:P37010) (115 aa) fasta scores: E(): 5e-40, 88.79% id in 116 aa, and to Salmonella typhimurium, and Salmonella typhi putative glutaredoxin protein ydhd or stm1433 or sty1689 SWALL:Q8XGR7 (EMBL:AE008762) (115 aa) fasta scores: E(): 1.5e-40, 90.51% id in 116 aa; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 0.536
nifS
Cysteine desulfurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
  
  
 0.521
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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