| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aguA | speA | ECA4273 | ECA3918 | Similar to Yersinia pestis hypothetical protein Ypo0939 SWALL:Q8ZHG0 (EMBL:AJ414145) (371 aa) fasta scores: E(): 1.3e-117, 75.47% id in 367 aa, and to Shewanella oneidensis conserved hypothetical protein so0887 SWALL:AAN53963 (EMBL:AE015534) (349 aa) fasta scores: E(): 3.9e-99, 67.33% id in 349 aa. | Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. | 0.989 |
| aguA | speD | ECA4273 | ECA3334 | Similar to Yersinia pestis hypothetical protein Ypo0939 SWALL:Q8ZHG0 (EMBL:AJ414145) (371 aa) fasta scores: E(): 1.3e-117, 75.47% id in 367 aa, and to Shewanella oneidensis conserved hypothetical protein so0887 SWALL:AAN53963 (EMBL:AE015534) (349 aa) fasta scores: E(): 3.9e-99, 67.33% id in 349 aa. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.575 |
| aguA | speE | ECA4273 | ECA3333 | Similar to Yersinia pestis hypothetical protein Ypo0939 SWALL:Q8ZHG0 (EMBL:AJ414145) (371 aa) fasta scores: E(): 1.3e-117, 75.47% id in 367 aa, and to Shewanella oneidensis conserved hypothetical protein so0887 SWALL:AAN53963 (EMBL:AE015534) (349 aa) fasta scores: E(): 3.9e-99, 67.33% id in 349 aa. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.613 |
| expI | metK | ECA0105 | ECA3920 | Similar to Erwinia carotovora autoinducer synthesis protein CarI or HslI SWALL:CARI_ERWCA (SWALL:P33880) (216 aa) fasta scores: E(): 1.1e-85, 97.22% id in 216 aa, and to Erwinia carotovora autoinducer synthesis protein ExpI SWALL:EXPI_ERWCA (SWALL:P33882) (217 aa) fasta scores: E(): 9.2e-65, 72.94% id in 207 aa, and to Erwinia chrysanthemi AhlI SWALL:Q8KUJ8 (EMBL:AF448800) (212 aa) fasta scores: E(): 6.5e-54, 62.26% id in 212 aa. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.947 |
| expI | speD | ECA0105 | ECA3334 | Similar to Erwinia carotovora autoinducer synthesis protein CarI or HslI SWALL:CARI_ERWCA (SWALL:P33880) (216 aa) fasta scores: E(): 1.1e-85, 97.22% id in 216 aa, and to Erwinia carotovora autoinducer synthesis protein ExpI SWALL:EXPI_ERWCA (SWALL:P33882) (217 aa) fasta scores: E(): 9.2e-65, 72.94% id in 207 aa, and to Erwinia chrysanthemi AhlI SWALL:Q8KUJ8 (EMBL:AF448800) (212 aa) fasta scores: E(): 6.5e-54, 62.26% id in 212 aa. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.944 |
| expI | speE | ECA0105 | ECA3333 | Similar to Erwinia carotovora autoinducer synthesis protein CarI or HslI SWALL:CARI_ERWCA (SWALL:P33880) (216 aa) fasta scores: E(): 1.1e-85, 97.22% id in 216 aa, and to Erwinia carotovora autoinducer synthesis protein ExpI SWALL:EXPI_ERWCA (SWALL:P33882) (217 aa) fasta scores: E(): 9.2e-65, 72.94% id in 207 aa, and to Erwinia chrysanthemi AhlI SWALL:Q8KUJ8 (EMBL:AF448800) (212 aa) fasta scores: E(): 6.5e-54, 62.26% id in 212 aa. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.944 |
| hisD | metK | ECA2583 | ECA3920 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.667 |
| hisD | sfcA | ECA2583 | ECA2831 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | Similar to Escherichia coli NAD-dependent malic enzyme SfcA or MaeA or b1479 SWALL:MAO1_ECOLI (SWALL:P26616) (574 aa) fasta scores: E(): 1.9e-174, 78.01% id in 564 aa; Belongs to the malic enzymes family. | 0.532 |
| hisD | speD | ECA2583 | ECA3334 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.548 |
| hisD | trpS | ECA2583 | ECA4087 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.653 |
| masA | mtnA | ECA3486 | ECA3477 | Enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | Putative translation initiation factor EIF-2B; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.943 |
| masA | speD | ECA3486 | ECA3334 | Enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.660 |
| masA | speE | ECA3486 | ECA3333 | Enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.752 |
| metK | expI | ECA3920 | ECA0105 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Similar to Erwinia carotovora autoinducer synthesis protein CarI or HslI SWALL:CARI_ERWCA (SWALL:P33880) (216 aa) fasta scores: E(): 1.1e-85, 97.22% id in 216 aa, and to Erwinia carotovora autoinducer synthesis protein ExpI SWALL:EXPI_ERWCA (SWALL:P33882) (217 aa) fasta scores: E(): 9.2e-65, 72.94% id in 207 aa, and to Erwinia chrysanthemi AhlI SWALL:Q8KUJ8 (EMBL:AF448800) (212 aa) fasta scores: E(): 6.5e-54, 62.26% id in 212 aa. | 0.947 |
| metK | hisD | ECA3920 | ECA2583 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.667 |
| metK | speD | ECA3920 | ECA3334 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.986 |
| metK | speE | ECA3920 | ECA3333 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.610 |
| metK | trpS | ECA3920 | ECA4087 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.680 |
| mtnA | masA | ECA3477 | ECA3486 | Putative translation initiation factor EIF-2B; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | Enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.943 |
| mtnA | speD | ECA3477 | ECA3334 | Putative translation initiation factor EIF-2B; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.604 |
