STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3389Similar to Ralstonia solanacearum probable integrase/recombinase protein rsp0090 or rs05531 SWALL:Q8XTL6 (EMBL:AL646076) (347 aa) fasta scores: E(): 3e-54, 48.59% id in 321 aa, and to Bacillus halodurans integrase/recombinase codv or bh2465 SWALL:Q9KA25 (EMBL:AP001515) (303 aa) fasta scores: E(): 1.1e-28, 35.85% id in 304 aa. Also similar to ECA3399 (93.824% id), ECA3406 (91.150% id), ECA3415 (91.150% id), ECA4283 (68.421% id), ECA4292 (68.421% id); Belongs to the 'phage' integrase family. (340 aa)    
Predicted Functional Partners:
ECA3390
DnaG primase-like protein; Similar to Photorhabdus luminescens DnaG primase-like dnaG SWALL:AAN64202 (EMBL:AY144117) (925 aa) fasta scores: E(): 2.5e-133, 71.76% id in 928 aa, and to the N-terminal region of Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri DNA primase dnag or dnap or parb or b3066 or z4419 or ecs3949 or sf3107 SWALL:PRIM_ECOLI (SWALL:P02923) (581 aa) fasta scores: E(): 2.7e-13, 29.1% id in 378 aa. Also similar to ECA3400, (82.939% id), ECA3407 (85.082% id), ECA3416 (85.082% id), ECA4282 (80.041% id), and to ECA4291 (80.041% id).
 
     0.742
ECA2637
Similar to Bacteriophage P2 integrase Int SWALL:VINT_BPP2 (SWALL:P36932) (337 aa) fasta scores: E(): 1.2e-68, 54.29% id in 326 aa; Belongs to the 'phage' integrase family.
  
   
 0.666
ftsK
Similar to Escherichia coli cell division protein FtsK or b0890 SWALL:FTSK_ECOLI (SWALL:P46889) (1329 aa) fasta scores: E(): 3.8e-163, 53.6% id in 1347 aa.
  
   
 0.559
recR
Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
   
 0.540
ECA3388
Hypothetical protein; No significant database matches.
       0.463
ECA3391
Putative prophage regulatory ptotein; Similar to Escherichia coli O157:H7 similar to DicA, regulator of dicB, encoded within cryptic prophage cp-933m z1333 or ecs1069 SWALL:Q8XD66 (EMBL:AE005287) (132 aa) fasta scores: E(): 0.00065, 33.66% id in 101 aa.
       0.451
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
   
 0.409
xerC
Integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the t [...]
 
 
 
0.408
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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