Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ECA3390DnaG primase-like protein; Similar to Photorhabdus luminescens DnaG primase-like dnaG SWALL:AAN64202 (EMBL:AY144117) (925 aa) fasta scores: E(): 2.5e-133, 71.76% id in 928 aa, and to the N-terminal region of Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri DNA primase dnag or dnap or parb or b3066 or z4419 or ecs3949 or sf3107 SWALL:PRIM_ECOLI (SWALL:P02923) (581 aa) fasta scores: E(): 2.7e-13, 29.1% id in 378 aa. Also similar to ECA3400, (82.939% id), ECA3407 (85.082% id), ECA3416 (85.082% id), ECA4282 (80.041% id), and to ECA4291 (80.041% id). (968 aa)    
Predicted Functional Partners:
ECA3389
Similar to Ralstonia solanacearum probable integrase/recombinase protein rsp0090 or rs05531 SWALL:Q8XTL6 (EMBL:AL646076) (347 aa) fasta scores: E(): 3e-54, 48.59% id in 321 aa, and to Bacillus halodurans integrase/recombinase codv or bh2465 SWALL:Q9KA25 (EMBL:AP001515) (303 aa) fasta scores: E(): 1.1e-28, 35.85% id in 304 aa. Also similar to ECA3399 (93.824% id), ECA3406 (91.150% id), ECA3415 (91.150% id), ECA4283 (68.421% id), ECA4292 (68.421% id); Belongs to the 'phage' integrase family.
 
     0.742
ECA0519
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
 
 0.733
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
  
 0.687
engA
Probable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
   
  
 0.590
rpoD
RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
 
  
 0.571
ECA3391
Putative prophage regulatory ptotein; Similar to Escherichia coli O157:H7 similar to DicA, regulator of dicB, encoded within cryptic prophage cp-933m z1333 or ecs1069 SWALL:Q8XD66 (EMBL:AE005287) (132 aa) fasta scores: E(): 0.00065, 33.66% id in 101 aa.
       0.540
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
  
 
0.482
priB
Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
   
 
 0.478
rpoH
RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
  
  
 0.471
rpoS
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
  
  
 0.457
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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