STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3416DnaG primase-like protein; Similar to Photorhabdus luminescens DnaG primase-like dnaG SWALL:AAN64202 (EMBL:AY144117) (925 aa) fasta scores: E(): 2e-145, 73.72% id in 921 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri DNA primase DnaG or DnaP or ParB or b3066 or z4419 or ecs3949 or sf3107 SWALL:PRIM_ECOLI (SWALL:P02923) (581 aa) fasta scores: E(): 1.2e-13, 27.89% id in 423 aa. Also similar to ECA3390, (85.082% id), ECA3400 (86.812% id), ECA3407 (100.000% id), ECA4282 (87.010% id), and to ECA4291 (87.010% id). (959 aa)    
Predicted Functional Partners:
ECA3415
Probable integrase/recombinase; Similar to Photorhabdus luminescens Int SWALL:AAN64203 (EMBL:AY144117) (465 aa) fasta scores: E(): 7.7e-79, 63.66% id in 322 aa, and to Ralstonia solanacearum probable integrase/recombinase protein rsp0090 or rs05531 SWALL:Q8XTL6 (EMBL:AL646076) (347 aa) fasta scores: E(): 3e-52, 48.28% id in 321 aa. Also similar to ECA3389 (91.150% id), ECA3399 (93.003% id), ECA3406 (100.000% id), ECA4283 (66.765% id), ECA4292 (66.765% id).
 
     0.765
ECA3417
Putative phage regulatory protein; Similar to Vibrio phage CTX RstR SWALL:Q8LTJ3 (EMBL:AF511000) (112 aa) fasta scores: E(): 0.024, 32% id in 100 aa, and to Stigmatella aurantiaca putative transcriptional repressor SWALL:Q93TW4 (EMBL:AF319998) (119 aa) fasta scores: E(): 0.001, 30.35% id in 112 aa.
 
     0.715
ECA0519
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
 
 0.596
engA
Probable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
   
  
 0.590
rpoD
RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
 
  
 0.570
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
  
 0.532
rpoH
RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
  
  
 0.471
rpoS
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
  
  
 0.457
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
   0.418
ECA3418
Conserved hypothetical protein; Similar to Photorhabdus luminescens Orf8 SWALL:AAN64200 (EMBL:AY144117) (106 aa) fasta scores: E(): 2.9e-08, 39.77% id in 88 aa, and to Salmonella typhimurium putative cytoplasmic protein stm0296 SWALL:Q8ZRK7 (EMBL:AE008708) (82 aa) fasta scores: E(): 1.7e-08, 40% id in 65 aa.
       0.410
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.