STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (417 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.999
putA
Bifunctional PutA protein [includes: proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
    
 0.951
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
 
  
 0.897
glnA
Glutamine synthetase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri glutamine synthetase GlnA or b3870 or c4819 or z5406 or ecs4792 or sf3940 SWALL:GLNA_ECOLI (SWALL:P06711) (468 aa) fasta scores: E(): 3e-170, 90.17% id in 468 aa.
    
 0.862
atpA
ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
 
    
 0.854
gdhA
Similar to Escherichia coli NADP-specific glutamate dehydrogenase GdhA or b1761 SWALL:DHE4_ECOLI (SWALL:P00370) (447 aa) fasta scores: E(): 7.7e-145, 85.01% id in 447 aa; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.839
gltD
Similar to Escherichia coli glutamate synthase [NADPH] small chain GltD or AspB or b3213 SWALL:GLTD_ECOLI (SWALL:P09832) (471 aa) fasta scores: E(): 5e-153, 85.56% id in 471 aa.
    
 0.809
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.772
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
   
   0.706
argH
Similar to Escherichia coli argininosuccinate lyase ArgH or b3960 SWALL:ARLY_ECOLI (SWALL:P11447) (457 aa) fasta scores: E(): 1.4e-155, 85.52% id in 456 aa.
 
   
 0.689
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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