STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crlCurlin genes transcriptional activator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. (124 aa)    
Predicted Functional Partners:
ECA3465
Similar to Yersinia pestis hypothetical protein y0964 SWALL:AAM84545 (EMBL:AE013700) (421 aa) fasta scores: E(): 1.4e-127, 71.56% id in 415 aa, and to Salmonella typhimurium hypothetical protein yafa or stm0318 SWALL:YAFA_SALTY (SWALL:P37722) (414 aa) fasta scores: E(): 8.4e-120, 66.18% id in 417 aa; Belongs to the UPF0255 family.
 
     0.816
ECA3599
Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O6 hypothetical protein ytfk or b4217 or c5315 SWALL:YTFK_ECOLI (SWALL:P39318) (68 aa) fasta scores: E(): 2.1e-19, 79.1% id in 67 aa, and to Yersinia pestis hypothetical protein ypo3527 or y0656 SWALL:AAM84244 (EMBL:AJ414157) (70 aa) fasta scores: E(): 6.1e-19, 77.27% id in 66 aa.
  
     0.774
viaA
Similar to Escherichia coli O6 hypothetical protein YieM SWALL:AAN83105 (EMBL:AE016769) (483 aa) fasta scores: E(): 1.1e-124, 63.03% id in 487 aa.
  
     0.769
zapC
Conserved hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
  
     0.758
atpI
ATP synthase protein I; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri ATP synthase protein I AtpI or UncI or b3739 or c4667 or sf3819 SWALL:ATPZ_ECOLI (SWALL:P03808) (125 aa) fasta scores: E(): 5.7e-21, 57.02% id in 121 aa.
  
     0.750
ilvM
Acetolactate synthase isozyme II small subunit; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri acetolactate synthase isozyme II small subunit IlvM or b3769 or c4691 or sf3844 SWALL:ILVM_ECOLI (SWALL:P13048) (86 aa) fasta scores: E(): 1.8e-18, 63.52% id in 85 aa.
  
     0.736
ECA0299
Conserved hypothetical protein; Similar to Yersinia pestis putative anti-sigma B factor antagonist ypo3571 SWALL:Q8ZB54 (EMBL:AJ414157) (100 aa) fasta scores: E(): 3.9e-18, 60.41% id in 96 aa, and to Escherichia coli, and Shigella flexneri hypothetical protein yrbb yrbb or b3191 or sf3231 SWALL:YRBB_ECOLI (SWALL:P45389) (97 aa) fasta scores: E(): 4.6e-11, 40.62% id in 96 aa.
  
     0.730
ECA1814
Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi hypothetical protein ycfp or stm1210 or sty1250 SWALL:Q8XGQ0 (EMBL:AE008752) (180 aa) fasta scores: E(): 8.5e-62, 82.77% id in 180 aa, and to Yersinia pestis hypothetical protein ypo1616 or y1776 SWALL:AAM85344 (EMBL:AJ414149) (180 aa) fasta scores: E(): 3.8e-61, 81.11% id in 180 aa; Belongs to the UPF0227 family.
  
     0.730
ECA2287
Conserved hypothetical protein; Similar to Salmonella enterica subsp. enterica serovar Typhi Ty2 hypothetical protein SWALL:AAO69255 (EMBL:AE016839) (83 aa) fasta scores: E(): 3.7e-19, 66.26% id in 83 aa, and to Yersinia pestis hypothetical protein ypo2217 ypo2217 or y2058 SWALL:Q8ZEF6 (EMBL:AJ414151) (83 aa) fasta scores: E(): 5e-19, 71.42% id in 77 aa.
  
     0.719
lapA
Putative membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.712
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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