Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA3005 | ECA3631 | ECA3005 | ECA3631 | Similar to Ralstonia solanacearum putative glutamine amidotransferase protein rsc0213 or rs00645 SWALL:Q8Y2W9 (EMBL:AL646058) (238 aa) fasta scores: E(): 9e-37, 45.37% id in 238 aa, and to Xylella fastidiosa GMP synthase xf0560 SWALL:Q9PFU7 (EMBL:AE003903) (240 aa) fasta scores: E(): 1.1e-28, 43.8% id in 242 aa. | Ham1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.910 |
| ECA3005 | apt | ECA3005 | ECA1175 | Similar to Ralstonia solanacearum putative glutamine amidotransferase protein rsc0213 or rs00645 SWALL:Q8Y2W9 (EMBL:AL646058) (238 aa) fasta scores: E(): 9e-37, 45.37% id in 238 aa, and to Xylella fastidiosa GMP synthase xf0560 SWALL:Q9PFU7 (EMBL:AE003903) (240 aa) fasta scores: E(): 1.1e-28, 43.8% id in 242 aa. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.929 |
| ECA3005 | gmk | ECA3005 | ECA0040 | Similar to Ralstonia solanacearum putative glutamine amidotransferase protein rsc0213 or rs00645 SWALL:Q8Y2W9 (EMBL:AL646058) (238 aa) fasta scores: E(): 9e-37, 45.37% id in 238 aa, and to Xylella fastidiosa GMP synthase xf0560 SWALL:Q9PFU7 (EMBL:AE003903) (240 aa) fasta scores: E(): 1.1e-28, 43.8% id in 242 aa. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.921 |
| ECA3005 | gpt | ECA3005 | ECA3466 | Similar to Ralstonia solanacearum putative glutamine amidotransferase protein rsc0213 or rs00645 SWALL:Q8Y2W9 (EMBL:AL646058) (238 aa) fasta scores: E(): 9e-37, 45.37% id in 238 aa, and to Xylella fastidiosa GMP synthase xf0560 SWALL:Q9PFU7 (EMBL:AE003903) (240 aa) fasta scores: E(): 1.1e-28, 43.8% id in 242 aa. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.929 |
| ECA3005 | guaA | ECA3005 | ECA3208 | Similar to Ralstonia solanacearum putative glutamine amidotransferase protein rsc0213 or rs00645 SWALL:Q8Y2W9 (EMBL:AL646058) (238 aa) fasta scores: E(): 9e-37, 45.37% id in 238 aa, and to Xylella fastidiosa GMP synthase xf0560 SWALL:Q9PFU7 (EMBL:AE003903) (240 aa) fasta scores: E(): 1.1e-28, 43.8% id in 242 aa. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.924 |
| ECA3005 | guaB | ECA3005 | ECA3209 | Similar to Ralstonia solanacearum putative glutamine amidotransferase protein rsc0213 or rs00645 SWALL:Q8Y2W9 (EMBL:AL646058) (238 aa) fasta scores: E(): 9e-37, 45.37% id in 238 aa, and to Xylella fastidiosa GMP synthase xf0560 SWALL:Q9PFU7 (EMBL:AE003903) (240 aa) fasta scores: E(): 1.1e-28, 43.8% id in 242 aa. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.958 |
| ECA3005 | guaC | ECA3005 | ECA3801 | Similar to Ralstonia solanacearum putative glutamine amidotransferase protein rsc0213 or rs00645 SWALL:Q8Y2W9 (EMBL:AL646058) (238 aa) fasta scores: E(): 9e-37, 45.37% id in 238 aa, and to Xylella fastidiosa GMP synthase xf0560 SWALL:Q9PFU7 (EMBL:AE003903) (240 aa) fasta scores: E(): 1.1e-28, 43.8% id in 242 aa. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.958 |
| ECA3005 | hpt | ECA3005 | ECA3328 | Similar to Ralstonia solanacearum putative glutamine amidotransferase protein rsc0213 or rs00645 SWALL:Q8Y2W9 (EMBL:AL646058) (238 aa) fasta scores: E(): 9e-37, 45.37% id in 238 aa, and to Xylella fastidiosa GMP synthase xf0560 SWALL:Q9PFU7 (EMBL:AE003903) (240 aa) fasta scores: E(): 1.1e-28, 43.8% id in 242 aa. | Similar to Salmonella typhimurium hypoxanthine phosphoribosyltransferase Hpt or stm0170 SWALL:HPRT_SALTY (SWALL:O33799) (178 aa) fasta scores: E(): 1.2e-54, 86.2% id in 174 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypoxanthine phosphoribosyltransferase Hpt or b0125 or c0154 or sf0122 SWALL:HPRT_ECOLI (SWALL:P36766) (178 aa) fasta scores: E(): 2.4e-54, 84.48% id in 174 aa; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.924 |
| ECA3005 | ushA | ECA3005 | ECA1184 | Similar to Ralstonia solanacearum putative glutamine amidotransferase protein rsc0213 or rs00645 SWALL:Q8Y2W9 (EMBL:AL646058) (238 aa) fasta scores: E(): 9e-37, 45.37% id in 238 aa, and to Xylella fastidiosa GMP synthase xf0560 SWALL:Q9PFU7 (EMBL:AE003903) (240 aa) fasta scores: E(): 1.1e-28, 43.8% id in 242 aa. | Similar to Escherichia coli protein UshA precursor [includes: UDP-sugar hydrolase and 5'-nucleotidase] UshA or b0480 SWALL:USHA_ECOLI (SWALL:P07024) (550 aa) fasta scores: E(): 1.6e-157, 71.5% id in 551 aa; Belongs to the 5'-nucleotidase family. | 0.906 |
| ECA3631 | ECA3005 | ECA3631 | ECA3005 | Ham1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Similar to Ralstonia solanacearum putative glutamine amidotransferase protein rsc0213 or rs00645 SWALL:Q8Y2W9 (EMBL:AL646058) (238 aa) fasta scores: E(): 9e-37, 45.37% id in 238 aa, and to Xylella fastidiosa GMP synthase xf0560 SWALL:Q9PFU7 (EMBL:AE003903) (240 aa) fasta scores: E(): 1.1e-28, 43.8% id in 242 aa. | 0.910 |
| ECA3631 | gpt | ECA3631 | ECA3466 | Ham1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.917 |
| ECA3631 | guaA | ECA3631 | ECA3208 | Ham1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.972 |
| ECA3631 | guaB | ECA3631 | ECA3209 | Ham1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.935 |
| ECA3631 | hpt | ECA3631 | ECA3328 | Ham1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Similar to Salmonella typhimurium hypoxanthine phosphoribosyltransferase Hpt or stm0170 SWALL:HPRT_SALTY (SWALL:O33799) (178 aa) fasta scores: E(): 1.2e-54, 86.2% id in 174 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypoxanthine phosphoribosyltransferase Hpt or b0125 or c0154 or sf0122 SWALL:HPRT_ECOLI (SWALL:P36766) (178 aa) fasta scores: E(): 2.4e-54, 84.48% id in 174 aa; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.909 |
| ECA3631 | ushA | ECA3631 | ECA1184 | Ham1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Similar to Escherichia coli protein UshA precursor [includes: UDP-sugar hydrolase and 5'-nucleotidase] UshA or b0480 SWALL:USHA_ECOLI (SWALL:P07024) (550 aa) fasta scores: E(): 1.6e-157, 71.5% id in 551 aa; Belongs to the 5'-nucleotidase family. | 0.900 |
| apt | ECA3005 | ECA1175 | ECA3005 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Similar to Ralstonia solanacearum putative glutamine amidotransferase protein rsc0213 or rs00645 SWALL:Q8Y2W9 (EMBL:AL646058) (238 aa) fasta scores: E(): 9e-37, 45.37% id in 238 aa, and to Xylella fastidiosa GMP synthase xf0560 SWALL:Q9PFU7 (EMBL:AE003903) (240 aa) fasta scores: E(): 1.1e-28, 43.8% id in 242 aa. | 0.929 |
| apt | deoD | ECA1175 | ECA0730 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase; Similar to Escherichia coli, and Escherichia coli O157:H7 purine nucleoside phosphorylase deoD or Pup or b4384 or z5986 or ecs5343 SWALL:DEOD_ECOLI (SWALL:P09743) (238 aa) fasta scores: E(): 2.1e-80, 89.07% id in 238 aa. | 0.919 |
| apt | gmk | ECA1175 | ECA0040 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.953 |
| apt | gpt | ECA1175 | ECA3466 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.939 |
| apt | guaA | ECA1175 | ECA3208 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.989 |
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