STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepDSimilar to Escherichia coli aminoacyl-histidine dipeptidase PepD or PepH or b0237 SWALL:PEPD_ECOLI (SWALL:P15288) (484 aa) fasta scores: E(): 1.4e-145, 77.27% id in 484 aa. (486 aa)    
Predicted Functional Partners:
pepA
Cytosolic aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.921
pepN
Similar to Escherichia coli aminopeptidase N PepN or b0932 SWALL:AMPN_ECOLI (SWALL:P04825) (869 aa) fasta scores: E(): 0, 75.66% id in 867 aa.
     
 0.918
gshB
Similar to Escherichia coli glutathione synthetase GshB or Gsh-II or b2947 SWALL:GSHB_ECOLI (SWALL:P04425) (316 aa) fasta scores: E(): 2.1e-100, 81.2% id in 314 aa; Belongs to the prokaryotic GSH synthase family.
     
 0.915
pepB
Peptidase B; Probably plays an important role in intracellular peptide degradation.
   
 
 0.914
gshA
Glutamate--cysteine ligase; Similar to Escherichia coli, and Escherichia coli O6 glutamate--cysteine ligase GshA or Gsh-I or b2688 or c3245 SWALL:GSH1_ECOLI (SWALL:P06980) (518 aa) fasta scores: E(): 1.3e-158, 73.15% id in 514 aa; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
   
 
 0.910
ggt
Similar to Escherichia coli gamma-glutamyltranspeptidase precursor Ggt or b3447 SWALL:GGT_ECOLI (SWALL:P18956) (580 aa) fasta scores: E(): 2.3e-93, 46.93% id in 571 aa, and to Pseudomonas sp. gamma-glutamyltranspeptidase precursor Ggt SWALL:GGT_PSESP (SWALL:P36267) (575 aa) fasta scores: E(): 1.2e-114, 56.17% id in 591 aa.
     
 0.909
chaC
Putative cation transport protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
  0.900
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.880
glyA2
Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.880
aatA
Similar to Rhizobium meliloti aspartate aminotransferase A AatA or r02325 or smc01578 SWALL:AATA_RHIME (SWALL:Q02635) (400 aa) fasta scores: E(): 5.9e-80, 50.62% id in 399 aa, and to Agrobacterium tumefaciens aspartate aminotransferase A AatA or atu4278 or agr_l_1171 SWALL:Q8U821 (EMBL:AE009356) (412 aa) fasta scores: E(): 7.9e-115, 72.04% id in 397 aa.
   
  0.814
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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