Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA3475Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi hypothetical protein yajd or stm0411 or sty0449 or t2452 SWALL:YAJD_SALTY (SWALL:P40777) (115 aa) fasta scores: E(): 3.7e-46, 91.3% id in 115 aa, and to Yersinia pestis hypothetical protein Ypo1179 SWALL:Q8ZGU8 (EMBL:AJ414146) (113 aa) fasta scores: E(): 3.6e-45, 87.61% id in 113 aa. (116 aa)    
Predicted Functional Partners:
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
   
  
 0.697
ECA1578
Conserved hypothetical protein; Similar to Yersinia pestis nucleoprotein/polynucleotide-associated enzyme y2589 SWALL:AAM86144 (EMBL:AE013861) (179 aa) fasta scores: E(): 8.1e-50, 93.29% id in 179 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein stm4192 or sty4409 SWALL:Q8XF14 (EMBL:AE008896) (179 aa) fasta scores: E(): 3.5e-48, 88.26% id in 179 aa.
  
     0.549
fadE
Similar to Escherichia coli acyl-coenzyme A dehydrogenase FadE or b0221 SWALL:FADE_ECOLI (SWALL:Q47146) (814 aa) fasta scores: E(): 0, 77.66% id in 815 aa.
       0.527
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.527
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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