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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pucGSimilar to Bacillus subtilis purine catabolism protein PucG SWALL:PUCG_BACSU (SWALL:O32148) (416 aa) fasta scores: E(): 1.9e-78, 52.73% id in 402 aa, and to Xanthomonas campestris serine-pyruvate aminotransferase xcc0283 SWALL:Q8PDQ2 (EMBL:AE012124) (418 aa) fasta scores: E(): 2.2e-93, 59.7% id in 407 aa. (414 aa)    
Predicted Functional Partners:
amaB
Similar to Bacillus stearothermophilus N-carbamoyl-L-amino acid hydrolase AmaB SWALL:AMB1_BACST (SWALL:P37113) (409 aa) fasta scores: E(): 1.6e-54, 40.69% id in 403 aa, and to Yersinia pestis putative N-carbamyl-L-amino acid amidohydrolase y0939 SWALL:AAM84520 (EMBL:AE013696) (431 aa) fasta scores: E(): 3.3e-109, 66.34% id in 419 aa.
 
 
  0.992
ECA3499
Probable amidase; Similar to Yersinia pestis probable amidase ypo3261 or y0928 SWALL:Q8ZBX3 (EMBL:AJ414156) (465 aa) fasta scores: E(): 5.1e-122, 70.11% id in 455 aa, and to Pseudomonas sp. biuret hydrolase atzE SWALL:Q936X3 (EMBL:U66917) (457 aa) fasta scores: E(): 2e-87, 53.09% id in 452 aa.
 
  0.936
gcvP
Putative glycine cleavage system P protein (glycine dehydrogenase [decarboxylating]); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.877
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.851
glyA2
Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.851
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
    
 0.825
fom1
Similar to Streptomyces wedmorensis phosphoenolpyruvate phosphomutase Fom1 SWALL:P96074 (EMBL:AB016934) (435 aa) fasta scores: E(): 6.1e-59, 54.26% id in 293 aa, and to Streptomyces hygroscopicus phosphoenolpyruvate phosphomutase BcpB SWALL:PEPM_STRHY (SWALL:P29247) (313 aa) fasta scores: E(): 2.7e-22, 35.39% id in 291 aa.
  
  
 0.807
ECA3492
Putative amino acid ABC transporter, ATP-binding protein; Similar to Bacillus stearothermophilus glutamine transport ATP-binding protein GlnQ SWALL:GLNQ_BACST (SWALL:P27675) (242 aa) fasta scores: E(): 3.8e-43, 52.72% id in 239 aa, and to Yersinia pestis putative amino acid ABC transporter, ATP-binding protein ypo3254 or glnq or y0935 SWALL:Q8ZBY0 (EMBL:AJ414156) (248 aa) fasta scores: E(): 5.2e-78, 89.79% id in 245 aa.
     
 0.649
ECA3493
Similar to Yersinia pestis putative amino acid ABC transporter, permease protein ypo3255 or y0934 SWALL:Q8ZBX9 (EMBL:AJ414156) (217 aa) fasta scores: E(): 2.3e-76, 88.47% id in 217 aa, and to Agrobacterium tumefaciens ABC transporter, membrane spanning protein atu1390 or agr_c_2569 SWALL:Q8UFK7 (EMBL:AE009100) (219 aa) fasta scores: E(): 2.6e-49, 59.9% id in 217 aa.
       0.638
ECA3494
Similar to Yersinia pestis putative amino acid ABC transporter, permease protein ypo3256 or y0933 SWALL:AAM84515 (EMBL:AJ414156) (222 aa) fasta scores: E(): 1.1e-67, 79.27% id in 222 aa, and to Agrobacterium tumefaciens ABC transporter, membrane spanning protein atu1389 or agr_c_2567 SWALL:Q8UFK8 (EMBL:AE009100) (223 aa) fasta scores: E(): 3.1e-43, 57.27% id in 213 aa.
       0.638
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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