STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3500Similar to Yersinia pestis hypothetical protein ypo3262 or y0927 SWALL:Q8ZBX2 (EMBL:AJ414156) (155 aa) fasta scores: E(): 2e-36, 73.17% id in 123 aa, and to Bradyrhizobium japonicum Blr1042 protein blr1042 SWALL:BAC46307 (EMBL:AP005938) (130 aa) fasta scores: E(): 3.8e-26, 57.6% id in 125 aa. (128 aa)    
Predicted Functional Partners:
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 0.988
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
  
 
 0.977
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
 
 0.962
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.958
ECA3499
Probable amidase; Similar to Yersinia pestis probable amidase ypo3261 or y0928 SWALL:Q8ZBX3 (EMBL:AJ414156) (465 aa) fasta scores: E(): 5.1e-122, 70.11% id in 455 aa, and to Pseudomonas sp. biuret hydrolase atzE SWALL:Q936X3 (EMBL:U66917) (457 aa) fasta scores: E(): 2e-87, 53.09% id in 452 aa.
 
    0.891
fumA
Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.874
sucA
2-oxoglutarate dehydrogenase E1 component; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 2-oxoglutarate dehydrogenase E1 component SucA or b0726 or c0803 or z0880 or ecs0751 SWALL:ODO1_ECOLI (SWALL:P07015) (933 aa) fasta scores: E(): 0, 83.42% id in 935 aa.
  
 0.813
ECA3497
Similar to Xanthomonas axonopodis gamma-glutamyltranspeptidase Ggt or xac0305 SWALL:Q8PQL8 (EMBL:AE011655) (526 aa) fasta scores: E(): 1.1e-98, 53.01% id in 530 aa, and to Vibrio cholerae gamma-glutamyltranspeptidase, putative vca0558 SWALL:Q9KM31 (EMBL:AE004386) (522 aa) fasta scores: E(): 2.1e-82, 48.24% id in 514 aa.
 
   
 0.752
ECA2794
Putative exported protein; Similar to Thermoanaerobacter tengcongensis major membrane immunogen tte2480 SWALL:Q8R7D5 (EMBL:AE013189) (138 aa) fasta scores: E(): 0.61, 35% id in 140 aa, and to Clostridium acetobutylicum uncharacterized conserved protein cac2767 SWALL:Q97FH2 (EMBL:AE007774) (133 aa) fasta scores: E(): 0.0033, 31.86% id in 91 aa.
  
 0.750
maeB
Similar to Escherichia coli NADP-dependent malic enzyme MaeB or b2463 SWALL:MAO2_ECOLI (SWALL:P76558) (759 aa) fasta scores: E(): 0, 84.32% id in 759 aa.
  
 
 0.729
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.