STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proVSimilar to Escherichia coli glycine betaine/L-proline transport ATP-binding protein ProV or b2677 SWALL:PROV_ECOLI (SWALL:P14175) (400 aa) fasta scores: E(): 2e-112, 80.95% id in 399 aa. (400 aa)    
Predicted Functional Partners:
proW
Similar to Escherichia coli glycine betaine/L-proline transport system permease protein ProW or b2678 SWALL:PROW_ECOLI (SWALL:P14176) (354 aa) fasta scores: E(): 1.7e-94, 79.61% id in 363 aa.
 
 0.999
proX
Similar to Escherichia coli, and Escherichia coli O157:H7 glycine betaine-binding periplasmic protein precursor ProX or ProU or b2679 or z3981 or ecs3542 SWALL:PROX_ECOLI (SWALL:P14177) (330 aa) fasta scores: E(): 2.6e-98, 75.74% id in 334 aa.
 
 0.999
mdlA
ATP-binding component of ABC transporter; Similar to Escherichia coli multidrug resistance-like ATP-binding protein MdlA or Mdl or b0448 SWALL:MDLA_ECOLI (SWALL:P77265) (590 aa) fasta scores: E(): 2.2e-169, 76.45% id in 582 aa; multidrug resistance-like ATP-binding protein mdla.
 
     
0.610
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]
     
 0.539
asr
Acid shock protein; Required for growth and/or survival at acidic conditions.
      
 0.530
ahpC
Alkyl hydroperoxide reductase C22 protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
      
 0.507
hemX
Similar to Escherichia coli putative uroporphyrin-III C-methyltransferase HemX or b3803 SWALL:HEMX_ECOLI (SWALL:P09127) (393 aa) fasta scores: E(): 5.1e-71, 60.54% id in 370 aa.
      
 0.499
hemY
Porphyrin biosynthetic protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri HemY protein HemY or b3802 or c4721 or z5316 or ecs4732 or sf3874 SWALL:HEMY_ECOLI (SWALL:P09128) (398 aa) fasta scores: E(): 1.3e-109, 73.02% id in 393 aa, and to Salmonella typhi porphyrin biosynthetic protein sty3624 SWALL:Q8Z398 (EMBL:AL627279) (399 aa) fasta scores: E(): 7e-108, 71.24% id in 393 aa.
      
 0.499
rpoB
DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.497
hemD
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
      
 0.497
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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