Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
emrASimilar to Erwinia chrysanthemi EmrA protein EmrA SWALL:Q93KB1 (EMBL:AJ410307) (391 aa) fasta scores: E(): 7.9e-104, 72.63% id in 391 aa, and to Escherichia coli multidrug resistance protein A EmrA or b2685 SWALL:EMRA_ECOLI (SWALL:P27303) (390 aa) fasta scores: E(): 5.7e-94, 68.28% id in 391 aa. (391 aa)    
Predicted Functional Partners:
emrB
Multidrug resistance protein B; Similar to Escherichia coli, and Escherichia coli O157:H7 multidrug resistance protein B EmrB or b2686 or z3987 or ecs3548 SWALL:EMRB_ECOLI (SWALL:P27304) (512 aa) fasta scores: E(): 5.1e-176, 83.92% id in 510 aa; Belongs to the major facilitator superfamily.
 
 
 0.993
oprJ
Similar to Pseudomonas aeruginosa outer membrane protein OprJ precursor OprJ or pa4597 SWALL:OPRJ_PSEAE (SWALL:Q51397) (479 aa) fasta scores: E(): 1.2e-94, 57.82% id in 460 aa, and to Pseudomonas putida TtgC SWALL:Q9WWZ8 (EMBL:AF031417) (484 aa) fasta scores: E(): 2.4e-70, 45.14% id in 474 aa, and to Pseudomonas aeruginosa outer membrane protein oprm precursor oprm or oprk or pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 1.9e-66, 46.78% id in 466 aa.
 
 0.861
ECA2932
Similar to Ralstonia solanacearum putative drug efflux lipoprotein rsc3208 or rs02424 SWALL:Q8XUI0 (EMBL:AL646074) (486 aa) fasta scores: E(): 4e-119, 69.19% id in 487 aa, and to Xanthomonas campestris outer membrane protein oprn or xcc0419 SWALL:Q8PDC1 (EMBL:AE012139) (490 aa) fasta scores: E(): 9.1e-110, 65.09% id in 487 aa.
 
 0.833
ECA0912
Similar to Yersinia pestis putative membrane transport protein ypo0009 SWALL:Q8ZJS7 (EMBL:AJ414141) (474 aa) fasta scores: E(): 7.2e-49, 33.76% id in 459 aa, and to Escherichia coli hypothetical transport protein YieO SWALL:YIEO_ECOLI (SWALL:P31474) (475 aa) fasta scores: E(): 6.1e-48, 32.59% id in 451 aa.
 
 
 0.792
mdtD
Similar to Escherichia coli putative drug transporter MdtD SWALL:BAC06610 (EMBL:AB089190) (471 aa) fasta scores: E(): 6.9e-129, 74.02% id in 462 aa, and to Yersinia pestis putative membrane protein yegb or ypo2850 or y1383 SWALL:Q8ZCV8 (EMBL:AJ414154) (465 aa) fasta scores: E(): 1.2e-127, 73.92% id in 464 aa.
 
 
 0.791
macB
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.718
ECA1808
Putative DNA-binding protein (pseudogene); Predicted helix-turn-helix motif with score 1004.000, SD 2.61 at aa 40-61, sequence LRREEVAALAGVGLTWYTWLEQ.
 
 
 0.717
tolC
Similar to Escherichia coli outer membrane protein TolC precursor TolC or MtcB or MukA or RefI or b3035 SWALL:TOLC_ECOLI (SWALL:P02930) (495 aa) fasta scores: E(): 4.1e-124, 75.32% id in 466 aa, and to Erwinia chrysanthemi outer membrane protein TolC SWALL:Q93AG1 (EMBL:AF421372) (472 aa) fasta scores: E(): 2.3e-128, 77.89% id in 466 aa.
  
 0.687
hasF
Similar to Pseudomonas fluorescens outer membrane protein HasF SWALL:Q9RHT0 (EMBL:AB023289) (442 aa) fasta scores: E(): 1.5e-85, 54.96% id in 433 aa, and to Erwinia chrysanthemi proteases secretion protein PrtF precursor prtF SWALL:PRTF_ERWCH (SWALL:P23598) (462 aa) fasta scores: E(): 2.1e-75, 48.82% id in 424 aa. Also similar to ECA2781 (48.956% identity in 431 aa overlap).
  
 0.687
prtF
Similar to Erwinia chrysanthemi proteases secretion protein PrtF precursor SWALL:PRTF_ERWCH (SWALL:P23598) (462 aa) fasta scores: E(): 3.6e-123, 73.25% id in 445 aa. Also similar to ECA1534 (48.956% in 431 aa overlap.
  
 0.687
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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