STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
emrBMultidrug resistance protein B; Similar to Escherichia coli, and Escherichia coli O157:H7 multidrug resistance protein B EmrB or b2686 or z3987 or ecs3548 SWALL:EMRB_ECOLI (SWALL:P27304) (512 aa) fasta scores: E(): 5.1e-176, 83.92% id in 510 aa; Belongs to the major facilitator superfamily. (511 aa)    
Predicted Functional Partners:
emrA
Similar to Erwinia chrysanthemi EmrA protein EmrA SWALL:Q93KB1 (EMBL:AJ410307) (391 aa) fasta scores: E(): 7.9e-104, 72.63% id in 391 aa, and to Escherichia coli multidrug resistance protein A EmrA or b2685 SWALL:EMRA_ECOLI (SWALL:P27303) (390 aa) fasta scores: E(): 5.7e-94, 68.28% id in 391 aa.
 
 
 0.993
emrR
Negative regulator of multidrug resistance; Similar to Erwinia chrysanthemi EmrR protein EmrR SWALL:Q93KB2 (EMBL:AJ410307) (170 aa) fasta scores: E(): 2.2e-50, 77.51% id in 169 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 transcriptional repressor MprA or EmrR or b2684 or c3237 or z3985 or ecs3546 SWALL:MPRA_ECOLI (SWALL:P24201) (176 aa) fasta scores: E(): 1.7e-45, 71.34% id in 171 aa.
 
   
 0.644
aaeA
Putative HlyD family secretion protein; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.633
ehpD
Similar to Pseudomonas aeruginosa phenazine/pyocyanine biosynthesis protein PhzF SWALL:PHZF_PSEAE (SWALL:O69754) (278 aa) fasta scores: E(): 2.2e-56, 54.96% id in 282 aa, and to Pantoea agglomerans EhpD SWALL:AAN40893 (EMBL:AF451953) (287 aa) fasta scores: E(): 8.8e-40, 46.12% id in 258 aa.
      
 0.530
pecS
Regulatory protein; Similar to Erwinia chrysanthemi regulatory protein PecS SWALL:PECS_ERWCH (SWALL:P42195) (166 aa) fasta scores: E(): 5.5e-25, 48.76% id in 162 aa.
     
 0.509
lacZ
Beta-galactosidase; Similar to Escherichia coli beta-galactosidase LacZ or b0344 SWALL:BGAL_ECOLI (SWALL:P00722) (1023 aa) fasta scores: E(): 0, 64.84% id in 1024 aa; Belongs to the glycosyl hydrolase 2 family.
      
 0.500
aaeX
Putative membrane protein; Similar to Serratia marcescens hypothetical 7.8 kDa protein yhcR SWALL:Q8RQS4 (EMBL:AB080601) (67 aa) fasta scores: E(): 3.5e-20, 80.64% id in 62 aa, and to Yersinia pestis putative membrane protein ypo3684 or y0179 SWALL:Q8ZAV0 (EMBL:AJ414158) (67 aa) fasta scores: E(): 5.7e-20, 76.56% id in 64 aa.
      
 0.475
nupC2
Nucleoside permease; Similar to Escherichia coli, and Escherichia coli O6 nucleoside permease NupC or Cru or b2393 or c2932 SWALL:NUPC_ECOLI (SWALL:P33031) (400 aa) fasta scores: E(): 1.2e-105, 71.75% id in 400 aa.
       0.439
oprJ
Similar to Pseudomonas aeruginosa outer membrane protein OprJ precursor OprJ or pa4597 SWALL:OPRJ_PSEAE (SWALL:Q51397) (479 aa) fasta scores: E(): 1.2e-94, 57.82% id in 460 aa, and to Pseudomonas putida TtgC SWALL:Q9WWZ8 (EMBL:AF031417) (484 aa) fasta scores: E(): 2.4e-70, 45.14% id in 474 aa, and to Pseudomonas aeruginosa outer membrane protein oprm precursor oprm or oprk or pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 1.9e-66, 46.78% id in 466 aa.
 
 
 0.414
tolC
Similar to Escherichia coli outer membrane protein TolC precursor TolC or MtcB or MukA or RefI or b3035 SWALL:TOLC_ECOLI (SWALL:P02930) (495 aa) fasta scores: E(): 4.1e-124, 75.32% id in 466 aa, and to Erwinia chrysanthemi outer membrane protein TolC SWALL:Q93AG1 (EMBL:AF421372) (472 aa) fasta scores: E(): 2.3e-128, 77.89% id in 466 aa.
  
 
 0.413
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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