Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA3516Putative tRNA/rRNA methyltransferase; Similar to Erwinia chrysanthemi YfiF protein YfiF SWALL:Q93KA9 (EMBL:AJ410308) (366 aa) fasta scores: E(): 4.2e-86, 72.06% id in 383 aa, and to Yersinia pestis putative tRNA/rRNA methyltransferase yfif or ypo3269 SWALL:Q8ZBW5 (EMBL:AJ414156) (388 aa) fasta scores: E(): 4.4e-89, 67.76% id in 394 aa; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (383 aa)    
Predicted Functional Partners:
ECA2003
Putative exported protein; Similar to Yersinia pestis hypothetical protein y2005 SWALL:AAM85571 (EMBL:AE013803) (898 aa) fasta scores: E(): 1e-188, 52.6% id in 865 aa, and to Escherichia coli O6 hypothetical protein ydbh or c1828 SWALL:AAN80292 (EMBL:AE016760) (879 aa) fasta scores: E(): 2.9e-148, 44.01% id in 861 aa.
  
     0.703
ECA0034
Putative exported protein; Similar to Yersinia pestis possible exported protein ypo0033 SWALL:Q8ZJQ9 (EMBL:AJ414141) (569 aa) fasta scores: E(): 1.9e-128, 55.37% id in 558 aa, and to Escherichia coli O6 hypothetical protein YicH SWALL:AAN82916 (EMBL:AE016769) (577 aa) fasta scores: E(): 5.3e-123, 48.92% id in 558 aa.
  
     0.692
holD
DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
    0.652
helD
Helicase IV; Similar to Escherichia coli helicase IV HelD or b0962 SWALL:HELD_ECOLI (SWALL:P15038) (684 aa) fasta scores: E(): 1.6e-197, 69.29% id in 684 aa.
  
     0.644
ECA0304
Similar to Yersinia pestis putative membrane protein ypo3565 SWALL:AAM83730 (EMBL:AJ414157) (134 aa) fasta scores: E(): 1.5e-41, 87.97% id in 133 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein YhcB SWALL:YHCB_ECOLI (SWALL:P39436) (134 aa) fasta scores: E(): 5.6e-34, 80.31% id in 127 aa.
  
     0.639
rof
Modulator of rho-dependent transcription termination; Similar to Escherichia coli, and Shigella flexneri Rof protein or b0189 or sf0179 SWALL:ROF_ECOLI (SWALL:P52098) (84 aa) fasta scores: E(): 3.4e-22, 70.23% id in 84 aa, and to Salmonella typhimurium modulator of rho-dependent transcription termination Rof or stm0237 SWALL:Q8ZRN4 (EMBL:AE008706) (86 aa) fasta scores: E(): 2.9e-20, 66.27% id in 86 aa.
  
     0.639
smp
Putative membrane protein; Similar to Escherichia coli, and Shigella flexneri protein Smp precursor Smp or b4387 or sf4419 SWALL:SMP_ECOLI (SWALL:P18838) (214 aa) fasta scores: E(): 3.9e-52, 65.72% id in 213 aa.
  
     0.633
pehS
Two-component sensor kinase, regulator of virulence determinants; Similar to Pectobacterium carotovorum subsp. carotovorum sensor protein PehS SWALL:Q9ZIN8 (EMBL:AF022772) (484 aa) fasta scores: E(): 6.6e-176, 92.35% id in 484 aa, and to Erwinia chrysanthemi PhoQ protein phoQ SWALL:CAD33238 (EMBL:AJ489252) (491 aa) fasta scores: E(): 4.1e-152, 76.97% id in 482 aa.
  
 
   0.630
dsbA
Similar to Erwinia carotovora thiol:disulfide interchange protein DsbA precursor SWALL:DSBA_ERWCA (SWALL:Q9RB10) (207 aa) fasta scores: E(): 1.2e-76, 98.55% id in 207 aa.
 
     0.616
lpoB
Putative lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family.
  
     0.616
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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