STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trxCThioredoxin 2; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri thioredoxin 2 TrxC or b2582 or c3107 or z3867 or ecs3448 or sf2644 SWALL:THI2_ECOLI (SWALL:P33636) (139 aa) fasta scores: E(): 1.5e-43, 74.81% id in 139 aa; Belongs to the thioredoxin family. (139 aa)    
Predicted Functional Partners:
ECA2649
Thioredoxin reductase.
 0.869
rhs
Putative RHS protein; Similar to Photorhabdus luminescens Rhs Rhs-corE SWALL:AAN64198 (EMBL:AY144117) (1469 aa) fasta scores: E(): 3.1e-128, 41.64% id in 1395 aa, and to Ralstonia solanacearum putative RHS-related transmembrane protein rsp1137 or rs05482 SWALL:Q8XQT2 (EMBL:AL646083) (1517 aa) fasta scores: E(): 3e-74, 32.03% id in 1330 aa.
    
   0.688
ECA4278
Rhs-family protein; Similar to Photorhabdus luminescens Rhs Rhs-corE SWALL:AAN64198 (EMBL:AY144117) (1469 aa) fasta scores: E(): 3.6e-127, 42.61% id in 1361 aa, and to Escherichia coli O157:H7 rhs core protein with extension ecs0605 SWALL:Q8X2J4 (EMBL:AP002552) (1616 aa) fasta scores: E(): 3.9e-80, 37.61% id in 1361 aa.
    
   0.688
grxA
Glutaredoxin 1; Similar to Escherichia coli, and Shigella flexneri glutaredoxin 1 GrxA or Grx or b0849 or sf0802 SWALL:GLR1_ECOLI (SWALL:P00277) (85 aa) fasta scores: E(): 6e-21, 69.88% id in 83 aa.
  
  
 0.665
katB
Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
   
 
 0.634
ahpC
Alkyl hydroperoxide reductase C22 protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.548
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.537
gor
Similar to Escherichia coli glutathione reductase Gor SWALL:GSHR_ECOLI (SWALL:P06715) (450 aa) fasta scores: E(): 3.8e-155, 86.66% id in 450 aa and to to Yersinia pestis glutathione reductase Gor SWALL:Q8ZA43 (EMBL:AJ414160) (450 aa) fasta scores: E(): 7.8e-158, 88.66% id in 450 aa.
  
 
 0.528
ECA3519
Putative acyl-CoA synthetase; Similar to Yersinia pestis putative acetyltransferase ypo3272 SWALL:Q8ZBW2 (EMBL:AJ414156) (880 aa) fasta scores: E(): 0, 79.56% id in 881 aa, and to Escherichia coli hypothetical protein yfiq or b2584 SWALL:YFIQ_ECOLI (SWALL:P76594) (886 aa) fasta scores: E(): 0, 76.84% id in 881 aa.
 
     0.517
dps
DNA protection during starvation protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
   
  
 0.513
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.