STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3528Similar to Yersinia pestis hypothetical protein ypo1069 or y3108 SWALL:Q8ZH42 (EMBL:AJ414146) (235 aa) fasta scores: E(): 1.1e-77, 80.34% id in 234 aa, and to Escherichia coli O6 hypothetical protein yaeb or c0236 SWALL:AAN78728 (EMBL:AE016755) (235 aa) fasta scores: E(): 1e-64, 69.65% id in 234 aa. (238 aa)    
Predicted Functional Partners:
rcsF
Stimulator of colanic acid capsule synthesis; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
       0.801
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
       0.544
metQ
Similar to Escherichia coli D-methionine-binding lipoprotein MetQ precursor MetQ or b0197 SWALL:METQ_ECOLI (SWALL:P28635) (271 aa) fasta scores: E(): 3.6e-88, 87.82% id in 271 aa; Belongs to the nlpA lipoprotein family.
       0.526
metN
D-methionine transport ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
       0.436
metI
Similar to Escherichia coli D-methionine transport system permease protein MetI or b0198 SWALL:METI_ECOLI (SWALL:P31547) (217 aa) fasta scores: E(): 1.6e-67, 90.32% id in 217 aa.
       0.418
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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