STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nlpDPutative cell wall degradation lipoprotein; Similar to Escherichia coli, and Shigella flexneri lipoprotein nlpd precursor NlpD or b2742 or sf2765 SWALL:NLPD_ECOLI (SWALL:P33648) (379 aa) fasta scores: E(): 3.1e-54, 57.66% id in 385 aa. (344 aa)    
Predicted Functional Partners:
rpoS
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
  
  
 0.922
amiB
Similar to Escherichia coli N-acetylmuramoyl-L-alanine amidase AmiB precursor AmiB or b4169 SWALL:AMIB_ECOLI (SWALL:P26365) (445 aa) fasta scores: E(): 5.9e-74, 65.34% id in 430 aa.
 
  
 0.739
hfq
Putative phage-related protein (host factor-I protein); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
 
    0.623
lepB
Similar to Escherichia coli signal peptidase I LepB or b2568 SWALL:LEP_ECOLI (SWALL:P00803) (324 aa) fasta scores: E(): 4.7e-93, 69.75% id in 324 aa; Belongs to the peptidase S26 family.
 
  
 0.620
amiC
Similar to Escherichia coli O6 N-acetylmuramoyl-L-alanine amidase amic precursor AmiC or b2817 or c3411 SWALL:AMIC_ECOLI (SWALL:Q46929) (417 aa) fasta scores: E(): 2.2e-113, 72.46% id in 414 aa, and to Yersinia pestis N-acetylmuramoyl-L-alanine amidase amic ypo1023 SWALL:Q8ZH85 (EMBL:AJ414146) (416 aa) fasta scores: E(): 1.3e-120, 77.31% id in 410 aa.
 
   
 0.551
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
    0.550
ECA3349
Similar to Yersinia pestis putative sigma 54 modulation protein ypo3279 SWALL:Q8ZBV5 (EMBL:AJ414156) (120 aa) fasta scores: E(): 3.7e-34, 84.95% id in 113 aa, and to Salmonella typhimurium, and Salmonella typhi ribosome associated factor, stabilizes ribosomes against dissociation yfia or stm2665 or sty2853 SWALL:Q8XEX6 (EMBL:AE008821) (112 aa) fasta scores: E(): 8.3e-31, 79.46% id in 112 aa.
  
  
 0.536
ptsN
Similar to Escherichia coli, and Shigella flexneri nitrogen regulatory IIA protein PtsN or RpoP SWALL:PTSN_ECOLI (SWALL:P31222) (163 aa) fasta scores: E(): 1.3e-46, 80.12% id in 156 aa, and to Yersinia pestis phosphotransferase system enzyme IIA PtsN SWALL:AAM83751 (EMBL:AE013615) (164 aa) fasta scores: E(): 6.1e-48, 81.01% id in 158 aa.
   
    0.527
tolB
TolB protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
      
 0.524
imp
Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
  
 0.515
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.