STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cysJSulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (609 aa)    
Predicted Functional Partners:
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
 
 0.999
cysI
Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 0.999
cysN
Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.979
cysD
Similar to Escherichia coli sulfate adenylyltransferase subunit 2 CysD or b2752 SWALL:CYSD_ECOLI (SWALL:P21156) (302 aa) fasta scores: E(): 5.1e-117, 92.05% id in 302 aa.
  
  
 0.979
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
 
 0.972
cysK
Cysteine synthase A; Similar to Escherichia coli, and Escherichia coli O157:H7 cysteine synthase A CysK or CysZ or b2414 or z3680 or ecs3286 SWALL:CYSK_ECOLI (SWALL:P11096) (322 aa) fasta scores: E(): 1.4e-100, 89.13% id in 322 aa; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.946
ECA1156
Similar to Yersinia pestis putative pyridoxal-phosphate dependent protein ypo3147 or y1037 SWALL:Q8ZC75 (EMBL:AJ414155) (346 aa) fasta scores: E(): 1.4e-117, 83.47% id in 345 aa, and to Salmonella typhimurium putative cysteine synthase/cystathionine beta-synthase stm0458 SWALL:Q8ZRB5 (EMBL:AE008717) (351 aa) fasta scores: E(): 1.6e-105, 76.38% id in 343 aa.
  
 
 0.946
sseA
Similar to Escherichia coli 3-mercaptopyruvate sulfurtransferase SseA or b2521 SWALL:THTM_ECOLI (SWALL:P31142) (280 aa) fasta scores: E(): 2.5e-67, 59.19% id in 272 aa.
    
 0.932
ECA2536
Similar to Yersinia pestis putative iron-sulfur binding protein ypo1417 or y2752 SWALL:Q8ZG89 (EMBL:AJ414148) (370 aa) fasta scores: E(): 1.8e-107, 70.76% id in 366 aa, and to Salmonella typhimurium putative iron-sulfur protein stm1060 SWALL:Q8ZQ74 (EMBL:AE008746) (369 aa) fasta scores: E(): 1.3e-97, 65.04% id in 369 aa.
   
 
 0.923
ECA0070
Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
   
    0.921
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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