Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA3552Similar to Prevotella ruminicola polygalacturonase SWALL:Q9WXE7 (EMBL:AB022865) (494 aa) fasta scores: E(): 3.9e-17, 23.87% id in 423 aa, and to Agrobacterium tumefaciens polygalacturonase atu4560 or agr_l_619 SWALL:Q8U794 (EMBL:AE009384) (453 aa) fasta scores: E(): 2.8e-56, 36.03% id in 444 aa; Belongs to the glycosyl hydrolase 28 family. (448 aa)    
Predicted Functional Partners:
pemA
Similar to Erwinia chrysanthemi pectinesterase a precursor PemA or Pem SWALL:PMEA_ERWCH (SWALL:P07863) (366 aa) fasta scores: E(): 3.5e-98, 70.47% id in 359 aa.
 
  
 0.789
pehA
Endo-polygalacturonase; Similar to Erwinia carotovora endo-polygalacturonase precursor PehA SWALL:PGL2_ERWCA (SWALL:P26509) (402 aa) fasta scores: E(): 1.4e-143, 97.76% id in 402 aa, and to Erwinia carotovora Peh precursor SWALL:Q9S5V7 (EMBL:AB022681) (402 aa) fasta scores: E(): 1.3e-140, 95.77% id in 402 aa; Belongs to the glycosyl hydrolase 28 family.
  
  
  0.788
ECA3553
Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri putative 6-pyruvoyl tetrahydrobiopterin synthase YgcM or b2765 or z4075 or ecs3620 or sf2781 SWALL:PTPS_ECOLI (SWALL:Q46903) (121 aa) fasta scores: E(): 8.1e-44, 86.66% id in 120 aa.
       0.678
ECA3749
Similar to Erwinia chrysanthemi RhiN protein RhiN SWALL:CAC83616 (EMBL:AJ292045) (379 aa) fasta scores: E(): 1.8e-53, 45.01% id in 311 aa, and to Agrobacterium tumefaciens hypothetical protein atu4561 atu4561 or agr_l_618 SWALL:Q8U793 (EMBL:AE009384) (397 aa) fasta scores: E(): 4.9e-74, 53.46% id in 361 aa. Also similar to ECA3559 (RhiN) (43.810% id. in 315 aa overlap).
 
   
 0.648
kduI1
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
   
 0.636
kduI2
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
   
 0.632
pmeB
Similar to Erwinia chrysanthemi pectinesterase B precursor PemB SWALL:PMEB_ERWCH (SWALL:Q47474) (433 aa) fasta scores: E(): 8.6e-100, 65.48% id in 394 aa, and to Erwinia carotovora pectinesterase b pemB SWALL:PMEB_ERWCA (SWALL:P55743) (178 aa) fasta scores: E(): 7.6e-61, 91.47% id in 176 aa.
 
  
 0.611
uxaC
Uronate isomerase; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri uronate isomerase UxaC or b3092 or c3850 or sf3132 SWALL:UXAC_ECOLI (SWALL:P42607) (470 aa) fasta scores: E(): 8.6e-183, 89.33% id in 469 aa.
 
  
 0.607
rhiN
Similar to Erwinia chrysanthemi RhiN protein RhiN SWALL:CAC83616 (EMBL:AJ292045) (379 aa) fasta scores: E(): 9e-146, 87.07% id in 379 aa, and to Salmonella typhimurium putative cytoplasmic protein stm1911 SWALL:Q8ZNU8 (EMBL:AE008785) (379 aa) fasta scores: E(): 1.5e-128, 75.72% id in 379 aa. Also similar to ECA3749 (43.810% id. in 315 aa overlap).
 
   
 0.573
paeY
Similar to Erwinia chrysanthemi pectin acetylesterase PaeY SWALL:O32563 (EMBL:Y09828) (551 aa) fasta scores: E(): 8.8e-135, 61.07% id in 542 aa.
 
 0.559
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (14%) [HD]