Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA3557Metallo hydrolase; Similar to Erwinia chrysanthemi metallo hydrolase precursor Meh SWALL:CAC83617 (EMBL:AJ292045) (324 aa) fasta scores: E(): 1.8e-68, 56% id in 325 aa, and to Plesiomonas sp. DLL-1 methyl parathion degrading protein SWALL:Q93SP1 (EMBL:AY029773) (341 aa) fasta scores: E(): 5e-49, 47.41% id in 310 aa. Also similar to ECA3555 (52.761% id. in 326 aa overlap). (329 aa)    
Predicted Functional Partners:
ECA3558
Short chain dehydrogenase; Similar to Photorhabdus luminescens Orf29 SWALL:AAO17195 (EMBL:AF346500) (248 aa) fasta scores: E(): 6e-74, 81.04% id in 248 aa, and to Escherichia coli hypothetical oxidoreductase ygff or b2902 SWALL:YGFF_ECOLI (SWALL:P52037) (247 aa) fasta scores: E(): 1.5e-55, 63.26% id in 245 aa.
   
  0.776
ECA3556
LysR-family transcriptional regulator; Similar to Pseudomonas aeruginosa MexT protein MexT SWALL:O87785 (EMBL:AJ007825) (304 aa) fasta scores: E(): 3.2e-33, 36.3% id in 303 aa, and to Burkholderia cepacia DntR SWALL:Q8VUD7 (EMBL:AF169302) (301 aa) fasta scores: E(): 5.8e-33, 35.88% id in 301 aa; Belongs to the LysR transcriptional regulatory family.
 
    0.706
smpA
Putative outer membrane lipopotein (small protein A); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
      
 0.530
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
 
 0.489
thiI
Thiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 0.460
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 0.449
ECA2545
Similar to Yersinia pestis putative exported protein ypo1408 or y2762 SWALL:Q8ZG97 (EMBL:AJ414148) (182 aa) fasta scores: E(): 4.6e-60, 82.41% id in 182 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein ycbk or b0926 or c1068 or z1273 or ecs1009 or sf0923 SWALL:YCBK_ECOLI (SWALL:P75848) (182 aa) fasta scores: E(): 5.1e-56, 78.57% id in 182 aa.
   
    0.428
ECA0705
Partial CDS. Similar to an internal region of Agrobacterium tumefaciens non-ribosomal peptide synthetase MtaD or atu3682 or agr_l_2311 SWALL:Q8U9P4 (EMBL:AE009297) (2399 aa) fasta scores: E(): 0.00074, 32.99% id in 97 aa, and to Anabaena sp. peptide synthetase all2648 SWALL:Q8YTR5 (EMBL:AP003590) (2588 aa) fasta scores: E(): 0.0032, 34.4% id in 93 aa.
   
 
 0.424
ehpR
Putative phenazine antibiotic biosynthesis protein; Required for resistance to the phenazine antibiotic.
  
 0.423
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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