Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA3563Conserved hypothetical protein; Similar to Xanthomonas axonopodis nonf-related protein NonF or xac3491 SWALL:Q8PGX1 (EMBL:AE011997) (226 aa) fasta scores: E(): 1.8e-58, 68.77% id in 221 aa, and to Rhizobium meliloti hypothetical protein rb0205 or smb20212 SWALL:Q92WX2 (EMBL:AL603642) (226 aa) fasta scores: E(): 3.3e-57, 66.96% id in 224 aa. (226 aa)    
Predicted Functional Partners:
calB
Similar to Pseudomonas sp. coniferyl aldehyde dehydrogenase CalB SWALL:CALB_PSESP (SWALL:O86447) (480 aa) fasta scores: E(): 1.4e-97, 55.5% id in 463 aa, and to Caulobacter crescentus probable coniferyl aldehyde dehydrogenase CalB or cc1849 SWALL:CALB_CAUCR (SWALL:Q9A777) (485 aa) fasta scores: E(): 2.5e-85, 50.96% id in 467 aa.
  
  0.730
ECA0452
Putative zinc-binding dehydrogenase; Similar to Pseudomonas aeruginosa hypothetical protein pa2197 SWALL:Q9I1S0 (EMBL:AE004646) (345 aa) fasta scores: E(): 1.9e-102, 75.94% id in 345 aa, and to Salmonella typhi putative NADP-dependent oxidoreductase sty1476 SWALL:Q8Z742 (EMBL:AL627270) (345 aa) fasta scores: E(): 1.7e-100, 76.23% id in 345 aa.
 
   0.647
gloB
Probable hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
    
 0.613
gloA
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 
 0.607
ECA2211
Copper-zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
  
 
 0.598
ECA2383
Putative isochorismatase; Similar to Pseudomonas aeruginosa probable hydrolase pa1202 SWALL:Q9I4D6 (EMBL:AE004550) (205 aa) fasta scores: E(): 3.9e-25, 41.17% id in 204 aa, and to Pseudomonas syringae isochorismatase family protein pspto1009 SWALL:AAO54542 (EMBL:AE016859) (208 aa) fasta scores: E(): 5.3e-24, 38.91% id in 203 aa.
 
    0.573
ECA2348
Conserved hypothetical protein; Similar to Salmonella typhimurium putative ser protein kinase yeag or stm1285 SWALL:Q8ZPW2 (EMBL:AE008755) (644 aa) fasta scores: E(): 0, 94.09% id in 644 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yeag or b1783 or c2188 or z2823 or ecs2492 SWALL:YEAG_ECOLI (SWALL:P77391) (644 aa) fasta scores: E(): 0, 94.09% id in 644 aa.
   
    0.551
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 
  0.531
ECA1856
Putative FAD-binding oxidase; Similar to Yersinia pestis hypothetical protein ypo2407 or y1932 SWALL:AAM85498 (EMBL:AJ414152) (1018 aa) fasta scores: E(): 0, 82.41% id in 1018 aa, and to Escherichia coli hypothetical protein ydij or b1687 SWALL:YDIJ_ECOLI (SWALL:P77748) (1018 aa) fasta scores: E(): 0, 79.05% id in 1017 aa.
    
  0.530
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
    
  0.525
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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