STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3563Conserved hypothetical protein; Similar to Xanthomonas axonopodis nonf-related protein NonF or xac3491 SWALL:Q8PGX1 (EMBL:AE011997) (226 aa) fasta scores: E(): 1.8e-58, 68.77% id in 221 aa, and to Rhizobium meliloti hypothetical protein rb0205 or smb20212 SWALL:Q92WX2 (EMBL:AL603642) (226 aa) fasta scores: E(): 3.3e-57, 66.96% id in 224 aa. (226 aa)    
Predicted Functional Partners:
calB
Similar to Pseudomonas sp. coniferyl aldehyde dehydrogenase CalB SWALL:CALB_PSESP (SWALL:O86447) (480 aa) fasta scores: E(): 1.4e-97, 55.5% id in 463 aa, and to Caulobacter crescentus probable coniferyl aldehyde dehydrogenase CalB or cc1849 SWALL:CALB_CAUCR (SWALL:Q9A777) (485 aa) fasta scores: E(): 2.5e-85, 50.96% id in 467 aa.
  
   0.670
ECA2211
Copper-zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
  
 
 0.559
ECA0452
Putative zinc-binding dehydrogenase; Similar to Pseudomonas aeruginosa hypothetical protein pa2197 SWALL:Q9I1S0 (EMBL:AE004646) (345 aa) fasta scores: E(): 1.9e-102, 75.94% id in 345 aa, and to Salmonella typhi putative NADP-dependent oxidoreductase sty1476 SWALL:Q8Z742 (EMBL:AL627270) (345 aa) fasta scores: E(): 1.7e-100, 76.23% id in 345 aa.
 
    0.555
ECA2383
Putative isochorismatase; Similar to Pseudomonas aeruginosa probable hydrolase pa1202 SWALL:Q9I4D6 (EMBL:AE004550) (205 aa) fasta scores: E(): 3.9e-25, 41.17% id in 204 aa, and to Pseudomonas syringae isochorismatase family protein pspto1009 SWALL:AAO54542 (EMBL:AE016859) (208 aa) fasta scores: E(): 5.3e-24, 38.91% id in 203 aa.
 
   0.497
ECA2348
Conserved hypothetical protein; Similar to Salmonella typhimurium putative ser protein kinase yeag or stm1285 SWALL:Q8ZPW2 (EMBL:AE008755) (644 aa) fasta scores: E(): 0, 94.09% id in 644 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yeag or b1783 or c2188 or z2823 or ecs2492 SWALL:YEAG_ECOLI (SWALL:P77391) (644 aa) fasta scores: E(): 0, 94.09% id in 644 aa.
   
    0.483
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 
 0.468
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
 
 0.464
osmC
Similar to Escherichia coli, and Shigella flexneri osmotically inducible protein C OsmC or b1482 or sf1743 SWALL:OSMC_ECOLI (SWALL:P23929) (142 aa) fasta scores: E(): 4.2e-45, 87.14% id in 140 aa.
 
    0.461
dkgA
Similar to Escherichia coli 2,5-diketo-D-gluconic acid reductase A DkgA or b3012 SWALL:DKGA_ECOLI (SWALL:Q46857) (275 aa) fasta scores: E(): 1e-80, 72.42% id in 272 aa. In Salmonella typhi this is a putative pseudogene but it is apparently intact here.
  
  
 0.432
ECA3561
Similar to Streptomyces antibioticus transcriptional regulatory protein AraB AbaB SWALL:ARAB_STRAT (SWALL:P52659) (301 aa) fasta scores: E(): 4e-16, 32.78% id in 302 aa, and to Streptomyces coelicolor putative LysR-family transcriptional regulator sco6801 or sc1a2.10 SWALL:Q9L231 (EMBL:AL939129) (300 aa) fasta scores: E(): 1.2e-09, 30.9% id in 288 aa.
       0.429
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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