Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (431 aa)    
Predicted Functional Partners:
pykF
Pyruvate kinase; Similar to Escherichia coli, and Escherichia coli O157:H7 pyruvate kinase I PykF or b1676 or z2704 or ecs2383 SWALL:KPY1_ECOLI (SWALL:P14178) (470 aa) fasta scores: E(): 4.4e-139, 84.68% id in 470 aa.
 
 0.993
pgi
Glucose-6-phosphate isomerase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucose-6-phosphate isomerase Pgi or b4025 or z5623 or ecs5008 SWALL:G6PI_ECOLI (SWALL:P11537) (549 aa) fasta scores: E(): 1.4e-193, 86.86% id in 548 aa.
  
 0.993
pykA
Pyruvate kinase II; Similar to Escherichia coli pyruvate kinase ii PykA or b1854 SWALL:KPY2_ECOLI (SWALL:P21599) (479 aa) fasta scores: E(): 2.7e-156, 91.23% id in 479 aa.
  
 0.992
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
  
 0.991
pgk
Phosphoglycerate kinase; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri phosphoglycerate kinase Pgk or b2926 or c3504 or sf2911 SWALL:PGK_ECOLI (SWALL:P11665) (386 aa) fasta scores: E(): 6.3e-125, 89.11% id in 386 aa.
 
 
 0.990
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
  
 
 0.984
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.980
fbaA
Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 0.980
ECA0339
Probable sugar-bisphosphate aldolase; Similar to Escherichia coli tagatose-1,6-bisphosphate aldolase GatY or b2096 SWALL:GATY_ECOLI (SWALL:P37192) (284 aa) fasta scores: E(): 1.8e-26, 36.36% id in 286 aa, and to Escherichia coli O6 putative aldolase c4484 SWALL:AAN82920 (EMBL:AE016769) (283 aa) fasta scores: E(): 7.5e-58, 59.01% id in 283 aa.
  
 0.973
talA
Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
   
 0.972
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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