STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpfATwo-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa. (933 aa)    
Predicted Functional Partners:
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
 
0.999
rcsC
Two-component system sensor protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
 
0.999
expA
Two-component response regulator; Similar to Erwinia carotovora ExpA protein SWALL:O50326 (EMBL:X95564) (218 aa) fasta scores: E(): 1.3e-77, 98.62% id in 218 aa, and to Escherichia coli, and Shigella flexneri response regulator UvrY or b1914 or sf1957 SWALL:UVRY_ECOLI (SWALL:P07027) (218 aa) fasta scores: E(): 3.5e-65, 83.87% id in 217 aa. The Erwinia carotovora ExpA is involved in the global control of virulence.
 
 0.999
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
 
 0.999
rcsB
Two-component response regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
  
 0.998
rcsD
Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
 
0.998
ECA1568
Putative chemotaxis signal transduction protein; Similar to Vibrio fischeri CheV SWALL:AAL86625 (EMBL:AY079167) (306 aa) fasta scores: E(): 1.6e-26, 34.36% id in 323 aa, and to Salmonella typhimurium putative chemotaxis signal transduction protein stm2314 SWALL:Q8ZNE6 (EMBL:AE008803) (333 aa) fasta scores: E(): 8.2e-81, 70.44% id in 318 aa.
  
 0.998
ECA3199
Putative membrane protein; Similar to Yersinia pestis HmsT or ypo0425 or y3756 SWALL:AAM87301 (EMBL:AF129277) (390 aa) fasta scores: E(): 1.1e-12, 28.21% id in 319 aa, and to Pseudomonas putida GGDEF domain protein pp3452 SWALL:AAN69054 (EMBL:AE016786) (363 aa) fasta scores: E(): 2.2e-12, 32.65% id in 245 aa.
 
 0.998
evr
Virulence regulator; Similar to Pectobacterium carotovorum subsp. carotovorum virulence regulator Evr SWALL:AAN86997 (EMBL:AY167733) (204 aa) fasta scores: E(): 4.8e-39, 92.98% id in 114 aa. This CDS is truncated at the N-terminus relative to its orthologue in Pectobacterium carotovorum subsp. carotovorum.
  
 0.997
ECA0933
LuxR-family transcriptional regulator; Similar to Photorhabdus luminescens Orf66 SWALL:AAO17220 (EMBL:AF346500) (227 aa) fasta scores: E(): 8.7e-29, 36.01% id in 211 aa, and to Vibrio cholerae transcriptional regulator, LuxR family vca1078 SWALL:Q9KKM5 (EMBL:AE004433) (319 aa) fasta scores: E(): 1.7e-06, 26.63% id in 214 aa.
  
 0.997
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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