Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
garKGlycerate kinase 2; Similar to Escherichia coli glycerate kinase 2 GarK or b3124 SWALL:GRK2_ECOLI (SWALL:P23524) (381 aa) fasta scores: E(): 6.4e-89, 70.5% id in 373 aa, and to Bacillus subtilis glycerate kinase GalxK or s14A SWALL:GRK_BACSU (SWALL:P42100) (382 aa) fasta scores: E(): 3.9e-78, 58.57% id in 379 aa; Belongs to the glycerate kinase type-1 family. (381 aa)    
Predicted Functional Partners:
garR
2-hydroxy-3-oxopropionate reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily.
  
 
 0.985
hprA
Glycerate dehydrogenase; Similar to Methylobacterium extorquens glycerate dehydrogenase HprA SWALL:DHGY_METEX (SWALL:Q59516) (313 aa) fasta scores: E(): 9.9e-43, 42.03% id in 314 aa, and to Haemophilus influenzae putative 2-hydroxyacid dehydrogenase Hi1556 hi1556 SWALL:YF56_HAEIN (SWALL:P45250) (315 aa) fasta scores: E(): 6.7e-68, 55.06% id in 316 aa; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
 0.958
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
     
 0.946
tkrA
2-ketogluconate reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
    
  0.944
gpmB
Probable phosphoglycerate mutase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri probable phosphoglycerate mutase GpmB or b4395 or z5997 or ecs5353 or sf4427 SWALL:GPMB_ECOLI (SWALL:P36942) (215 aa) fasta scores: E(): 1.6e-61, 74.07% id in 216 aa.
     
 0.885
ECA0489
Similar to Escherichia coli 2-hydroxy-3-oxopropionate reductase GlxR or GlxB1 or b0509 SWALL:GLXR_ECOLI (SWALL:P77161) (292 aa) fasta scores: E(): 4.9e-13, 26.16% id in 279 aa, and to Pseudomonas aeruginosa probable 3-hydroxyisobutyrate dehydrogenase pa3312 SWALL:Q9HYT2 (EMBL:AE004753) (296 aa) fasta scores: E(): 3.4e-17, 31.09% id in 283 aa.
  
 
 0.799
tadA
Putative cytidine and deoxycytidylate deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
 
 
    0.680
cdaR
Similar to Escherichia coli carbohydrate diacid regulator CdaR or SdaR or b0162 SWALL:CDAR_ECOLI (SWALL:P37047) (385 aa) fasta scores: E(): 1e-124, 82.03% id in 384 aa.
 
  
 0.588
birA
Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
   
    0.552
calB
Similar to Pseudomonas sp. coniferyl aldehyde dehydrogenase CalB SWALL:CALB_PSESP (SWALL:O86447) (480 aa) fasta scores: E(): 1.4e-97, 55.5% id in 463 aa, and to Caulobacter crescentus probable coniferyl aldehyde dehydrogenase CalB or cc1849 SWALL:CALB_CAUCR (SWALL:Q9A777) (485 aa) fasta scores: E(): 2.5e-85, 50.96% id in 467 aa.
   
 
 0.549
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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