STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
garR2-hydroxy-3-oxopropionate reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily. (294 aa)    
Predicted Functional Partners:
garK
Glycerate kinase 2; Similar to Escherichia coli glycerate kinase 2 GarK or b3124 SWALL:GRK2_ECOLI (SWALL:P23524) (381 aa) fasta scores: E(): 6.4e-89, 70.5% id in 373 aa, and to Bacillus subtilis glycerate kinase GalxK or s14A SWALL:GRK_BACSU (SWALL:P42100) (382 aa) fasta scores: E(): 3.9e-78, 58.57% id in 379 aa; Belongs to the glycerate kinase type-1 family.
  
 
 0.950
garL
2-dehydro-3-deoxyglucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
 
 
  0.944
tkrA
2-ketogluconate reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
 
  
  0.916
hprA
Glycerate dehydrogenase; Similar to Methylobacterium extorquens glycerate dehydrogenase HprA SWALL:DHGY_METEX (SWALL:Q59516) (313 aa) fasta scores: E(): 9.9e-43, 42.03% id in 314 aa, and to Haemophilus influenzae putative 2-hydroxyacid dehydrogenase Hi1556 hi1556 SWALL:YF56_HAEIN (SWALL:P45250) (315 aa) fasta scores: E(): 6.7e-68, 55.06% id in 316 aa; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.906
gudD
Glucarate dehydratase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucarate dehydratase GudD or b2787 or z4102 or ecs3647 SWALL:GUDH_ECOLI (SWALL:P76637) (445 aa) fasta scores: E(): 2.3e-156, 84.87% id in 443 aa.
 
    0.589
otnI
Putative isomerase; Catalyzes the isomerization of 2-oxo-tetronate to 3-oxo- tetronate.
  
 0.575
gudX
Similar to Escherichia coli glucarate dehydratase related protein GudX or b2788 SWALL:GUDX_ECOLI (SWALL:Q46915) (446 aa) fasta scores: E(): 1.7e-152, 81.83% id in 446 aa.
 
    0.555
fadB
Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
  
 0.485
fadJ
Putative fatty acid oxidation complex alpha subunit; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 0.485
ECA0338
Probable sugar-bisphosphate aldolase; Similar to Lactobacillus casei D-fructose-1,6-biphosphate aldolase sorG SWALL:Q9RGG1 (EMBL:AF129168) (276 aa) fasta scores: E(): 1.9e-37, 41.97% id in 274 aa, and to Escherichia coli O6 putative aldolase c4483 SWALL:AAN82919 (EMBL:AE016769) (286 aa) fasta scores: E(): 8.4e-89, 80.06% id in 286 aa.
 
    0.477
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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