STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
garL2-dehydro-3-deoxyglucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily. (256 aa)    
Predicted Functional Partners:
gudD
Glucarate dehydratase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucarate dehydratase GudD or b2787 or z4102 or ecs3647 SWALL:GUDH_ECOLI (SWALL:P76637) (445 aa) fasta scores: E(): 2.3e-156, 84.87% id in 443 aa.
 
 
 0.971
garR
2-hydroxy-3-oxopropionate reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily.
 
 
  0.944
garD
D-galactarate dehydratase; Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate.
 
 
  0.941
LfeW
Similar to Salmonella typhimurium putative mandelate racemase / muconate lactonizing enzyme family stm3697 SWALL:Q8ZL58 (EMBL:AE008872) (398 aa) fasta scores: E(): 9.9e-148, 92.96% id in 398 aa, and to Pseudomonas putida mandelate racemase mdlA SWALL:MANR_PSEPU (SWALL:P11444) (359 aa) fasta scores: E(): 1.3e-22, 28.32% id in 353 aa.
 
 
 0.933
gudX
Similar to Escherichia coli glucarate dehydratase related protein GudX or b2788 SWALL:GUDX_ECOLI (SWALL:Q46915) (446 aa) fasta scores: E(): 1.7e-152, 81.83% id in 446 aa.
 
 
 0.850
ECA0936
Similar to Escherichia coli glucarate dehydratase related protein GudX or b2788 SWALL:GUDX_ECOLI (SWALL:Q46915) (446 aa) fasta scores: E(): 1.4e-101, 55.7% id in 447 aa; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
 
 0.714
ECA0489
Similar to Escherichia coli 2-hydroxy-3-oxopropionate reductase GlxR or GlxB1 or b0509 SWALL:GLXR_ECOLI (SWALL:P77161) (292 aa) fasta scores: E(): 4.9e-13, 26.16% id in 279 aa, and to Pseudomonas aeruginosa probable 3-hydroxyisobutyrate dehydrogenase pa3312 SWALL:Q9HYT2 (EMBL:AE004753) (296 aa) fasta scores: E(): 3.4e-17, 31.09% id in 283 aa.
 
 
  0.700
garK
Glycerate kinase 2; Similar to Escherichia coli glycerate kinase 2 GarK or b3124 SWALL:GRK2_ECOLI (SWALL:P23524) (381 aa) fasta scores: E(): 6.4e-89, 70.5% id in 373 aa, and to Bacillus subtilis glycerate kinase GalxK or s14A SWALL:GRK_BACSU (SWALL:P42100) (382 aa) fasta scores: E(): 3.9e-78, 58.57% id in 379 aa; Belongs to the glycerate kinase type-1 family.
  
  
 0.457
ltnD
Putative oxidoreductase; Catalyzes oxidation of L-threonate to 2-oxo-tetronate. Can use either NAD(+) or NADP(+) as cosubstrate, with a preference for NAD(+).
 
    0.434
ECA0327
Similar to Yersinia pestis hypothetical protein ypo0659 SWALL:Q8ZI55 (EMBL:AJ414144) (260 aa) fasta scores: E(): 3.4e-92, 84.55% id in 259 aa, and to Escherichia coli hypothetical protein YgiD SWALL:YGID_ECOLI (SWALL:P24197) (271 aa) fasta scores: E(): 4.1e-81, 72.41% id in 261 aa.
  
  
 0.411
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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