STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
garL2-dehydro-3-deoxyglucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily. (256 aa)    
Predicted Functional Partners:
gudD
Glucarate dehydratase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucarate dehydratase GudD or b2787 or z4102 or ecs3647 SWALL:GUDH_ECOLI (SWALL:P76637) (445 aa) fasta scores: E(): 2.3e-156, 84.87% id in 443 aa.
 
 
 0.947
garR
2-hydroxy-3-oxopropionate reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily.
 
 
 0.941
gudX
Similar to Escherichia coli glucarate dehydratase related protein GudX or b2788 SWALL:GUDX_ECOLI (SWALL:Q46915) (446 aa) fasta scores: E(): 1.7e-152, 81.83% id in 446 aa.
 
 
 0.908
garD
D-galactarate dehydratase; Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate.
 
 
 0.873
ECA0489
Similar to Escherichia coli 2-hydroxy-3-oxopropionate reductase GlxR or GlxB1 or b0509 SWALL:GLXR_ECOLI (SWALL:P77161) (292 aa) fasta scores: E(): 4.9e-13, 26.16% id in 279 aa, and to Pseudomonas aeruginosa probable 3-hydroxyisobutyrate dehydrogenase pa3312 SWALL:Q9HYT2 (EMBL:AE004753) (296 aa) fasta scores: E(): 3.4e-17, 31.09% id in 283 aa.
 
 
 0.827
ECA0936
Similar to Escherichia coli glucarate dehydratase related protein GudX or b2788 SWALL:GUDX_ECOLI (SWALL:Q46915) (446 aa) fasta scores: E(): 1.4e-101, 55.7% id in 447 aa; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
 
 0.819
LfeW
Similar to Salmonella typhimurium putative mandelate racemase / muconate lactonizing enzyme family stm3697 SWALL:Q8ZL58 (EMBL:AE008872) (398 aa) fasta scores: E(): 9.9e-148, 92.96% id in 398 aa, and to Pseudomonas putida mandelate racemase mdlA SWALL:MANR_PSEPU (SWALL:P11444) (359 aa) fasta scores: E(): 1.3e-22, 28.32% id in 353 aa.
 
 
 0.673
ltnD
Putative oxidoreductase; Catalyzes oxidation of L-threonate to 2-oxo-tetronate. Can use either NAD(+) or NADP(+) as cosubstrate, with a preference for NAD(+).
 
 
 0.593
uxaA
Similar to Escherichia coli altronate hydrolase UxaA SWALL:UXAA_ECOLI (SWALL:P42604) (495 aa) fasta scores: E(): 4.1e-163, 80.24% id in 496 aa.
  
 
 0.515
ECA4077
Putative mandelate racemase / muconate lactonizing enzyme; Similar to Agrobacterium tumefaciens isomerase/lactonizing enzyme atu3453 or agr_l_2751 SWALL:Q8UAC1 (EMBL:AE009275) (407 aa) fasta scores: E(): 1.1e-110, 65.17% id in 379 aa, and to Sulfolobus tokodaii putative dgoa protein st2366 SWALL:Q96Y01 (EMBL:AP000989) (396 aa) fasta scores: E(): 2.9e-21, 27.64% id in 369 aa; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
 
 0.496
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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