STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
garDD-galactarate dehydratase; Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate. (524 aa)    
Predicted Functional Partners:
gudD
Glucarate dehydratase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucarate dehydratase GudD or b2787 or z4102 or ecs3647 SWALL:GUDH_ECOLI (SWALL:P76637) (445 aa) fasta scores: E(): 2.3e-156, 84.87% id in 443 aa.
 
 
 0.985
LfeW
Similar to Salmonella typhimurium putative mandelate racemase / muconate lactonizing enzyme family stm3697 SWALL:Q8ZL58 (EMBL:AE008872) (398 aa) fasta scores: E(): 9.9e-148, 92.96% id in 398 aa, and to Pseudomonas putida mandelate racemase mdlA SWALL:MANR_PSEPU (SWALL:P11444) (359 aa) fasta scores: E(): 1.3e-22, 28.32% id in 353 aa.
 
  
 0.902
garL
2-dehydro-3-deoxyglucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
 
 
 0.873
ECA0936
Similar to Escherichia coli glucarate dehydratase related protein GudX or b2788 SWALL:GUDX_ECOLI (SWALL:Q46915) (446 aa) fasta scores: E(): 1.4e-101, 55.7% id in 447 aa; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
 
 0.810
gudX
Similar to Escherichia coli glucarate dehydratase related protein GudX or b2788 SWALL:GUDX_ECOLI (SWALL:Q46915) (446 aa) fasta scores: E(): 1.7e-152, 81.83% id in 446 aa.
 
 
 0.810
uxaB2
Altronate oxidoreductase; Similar to Escherichia coli, and Escherichia coli O157:H7 altronate oxidoreductase UxaB or b1521 or z2184 or ecs2128 SWALL:UXAB_ECOLI (SWALL:P24214) (483 aa) fasta scores: E(): 2.9e-146, 72.67% id in 483 aa. Also similar to ECA0646 (69.278% id. in 485 aa overlap).
 
 
 0.765
uxaB1
Altronate oxidoreductase; Similar to Escherichia coli, and Escherichia coli O157:H7 altronate oxidoreductase UxaB or b1521 or z2184 or ecs2128 SWALL:UXAB_ECOLI (SWALL:P24214) (483 aa) fasta scores: E(): 2e-148, 72.54% id in 488 aa, and to Yersinia pestis altronate oxidoreductase UxaB SWALL:AAM87147 (EMBL:AJ414143) (483 aa) fasta scores: E(): 3e-163, 80.28% id in 487 aa. Also similar to ECA4383 (69.278% id. in 485 aa overlap); Belongs to the mannitol dehydrogenase family. UxaB subfamily.
 
 
 0.761
hpcH
Similar to Escherichia coli 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase HpcH or HpaI SWALL:HPAI_ECOLI (SWALL:Q47098) (262 aa) fasta scores: E(): 4.9e-22, 32.4% id in 250 aa; Belongs to the HpcH/HpaI aldolase family.
 
 
 0.740
ECA3763
Similar to Bacillus subtilis dihydrodipicolinate synthase DapA SWALL:DAPA_BACSU (SWALL:Q04796) (290 aa) fasta scores: E(): 2.9e-26, 34.16% id in 281 aa, and to Escherichia coli O6 putative dihydrodipicolinate synthase c0761 SWALL:AAN79234 (EMBL:AE016757) (295 aa) fasta scores: E(): 1.9e-75, 67.91% id in 293 aa; Belongs to the DapA family.
    
 0.661
uxaC
Uronate isomerase; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri uronate isomerase UxaC or b3092 or c3850 or sf3132 SWALL:UXAC_ECOLI (SWALL:P42607) (470 aa) fasta scores: E(): 8.6e-183, 89.33% id in 469 aa.
 
  
 0.646
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (16%) [HD]