STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3586Similar to Yersinia pestis hypothetical protein Ypo0652 SWALL:Q8ZI62 (EMBL:AJ414144) (435 aa) fasta scores: E(): 2.2e-84, 51.13% id in 442 aa, and to Escherichia coli hypothetical protein ygif or b3054 SWALL:YGIF_ECOLI (SWALL:P30871) (433 aa) fasta scores: E(): 2.1e-80, 48.86% id in 442 aa. (445 aa)    
Predicted Functional Partners:
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
       0.661
ECA3038
Putative membrane protein; Similar to Yersinia pestis hypothetical protein ypo2564 or y1623 SWALL:YP64_YERPE (SWALL:Q8ZDJ8) (151 aa) fasta scores: E(): 2.9e-52, 79.47% id in 151 aa, and to Photorhabdus temperata b2295 SWALL:AAN08358 (EMBL:AY137386) (151 aa) fasta scores: E(): 1.6e-45, 69.53% id in 151 aa.
  
     0.657
yihI
Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
   
 0.595
sixA
Similar to Escherichia coli phosphohistidine phosphatase SixA or b2340 SWALL:SIXA_ECOLI (SWALL:P76502) (161 aa) fasta scores: E(): 6.1e-35, 66.02% id in 156 aa.
 
     0.559
pspB
Phage shock protein B; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 phage shock protein B PspB or b1305 or c1775 or z2480 or ecs1882 SWALL:PSPB_ECOLI (SWALL:P23854) (74 aa) fasta scores: E(): 4.9e-18, 70.83% id in 72 aa.
  
     0.518
ccmH2
Cytochrome C-type biogenesis protein; Similar to the C-terminal half of Escherichia coli, and Shigella flexneri cytochrome C-type biogenesis protein CcmH precursor CcmH or b2194 or sf2278 SWALL:CCMH_ECOLI (SWALL:P33925) (350 aa) fasta scores: E(): 5.9e-35, 48.14% id in 216 aa.
  
     0.444
dsbB
Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
  
     0.440
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
  
   
 0.439
ECA2747
Similar to Escherichia coli 37 kDa nucleoid-associated protein yejk or b2186 SWALL:NA37_ECOLI (SWALL:P33920) (334 aa) fasta scores: E(): 2.6e-104, 80.53% id in 334 aa.
  
   
 0.438
ECA3587
Putative membrane protein; Similar to Yersinia pestis putative exported protein ypo0651 or y3528 SWALL:Q8ZI63 (EMBL:AJ414144) (207 aa) fasta scores: E(): 2.5e-57, 76.69% id in 206 aa, and to Salmonella typhimurium, and Salmonella typhi putative sh3 domain protein ygim or stm3203 or sty3382 SWALL:Q8XFH7 (EMBL:AE008847) (204 aa) fasta scores: E(): 1.4e-51, 71.84% id in 206 aa.
       0.435
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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