STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ccatRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (414 aa)    
Predicted Functional Partners:
birA
Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
  
 0.726
ECA3587
Putative membrane protein; Similar to Yersinia pestis putative exported protein ypo0651 or y3528 SWALL:Q8ZI63 (EMBL:AJ414144) (207 aa) fasta scores: E(): 2.5e-57, 76.69% id in 206 aa, and to Salmonella typhimurium, and Salmonella typhi putative sh3 domain protein ygim or stm3203 or sty3382 SWALL:Q8XFH7 (EMBL:AE008847) (204 aa) fasta scores: E(): 1.4e-51, 71.84% id in 206 aa.
  
  
 0.713
sspB
Stringent starvation protein B; Similar to Escherichia coli, and Escherichia coli O157:H7 stringent starvation protein B SspB or b3228 or z4586 or ecs4101 SWALL:SSPB_ECOLI (SWALL:P25663) (165 aa) fasta scores: E(): 3e-39, 71.42% id in 168 aa.
  
     0.685
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.668
ftsB
Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
 
    0.664
orn
Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
 
   
 0.657
holA
Similar to Escherichia coli DNA polymerase III, delta subunit HolA or b0640 SWALL:HOLA_ECOLI (SWALL:P28630) (343 aa) fasta scores: E(): 6.2e-94, 69.79% id in 341 aa.
 
   
 0.645
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
  
  
 0.620
rpmF
50S ribosomal protein L32; Similar to Escherichia coli, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri 50S ribosomal protein L32 RpmF or b1089 or z1728 or ecs1467 or stm1191 or sty1230 or sf1093 SWALL:RL32_ECOLI (SWALL:P02435) (56 aa) fasta scores: E(): 2.5e-18, 87.5% id in 56 aa; Belongs to the bacterial ribosomal protein bL32 family.
  
  
 0.615
ECA0975
Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family.
  
     0.614
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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