| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA1474 | hmpX | ECA1474 | ECA3251 | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein year or b1797 or z2839 or ecs2506 SWALL:YEAR_ECOLI (SWALL:P76248) (119 aa) fasta scores: E(): 3.1e-30, 66.66% id in 105 aa, and to Salmonella typhi hypothetical protein Sty1850 SWALL:Q8Z6D6 (EMBL:AL627271) (120 aa) fasta scores: E(): 5.8e-30, 65.71% id in 105 aa. | Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | 0.657 |
| ECA1474 | norV | ECA1474 | ECA0902 | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein year or b1797 or z2839 or ecs2506 SWALL:YEAR_ECOLI (SWALL:P76248) (119 aa) fasta scores: E(): 3.1e-30, 66.66% id in 105 aa, and to Salmonella typhi hypothetical protein Sty1850 SWALL:Q8Z6D6 (EMBL:AL627271) (120 aa) fasta scores: E(): 5.8e-30, 65.71% id in 105 aa. | Anaerobic nitric oxide reductase flavorubredoxin; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family. | 0.656 |
| ECA1474 | ytfE | ECA1474 | ECA3606 | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein year or b1797 or z2839 or ecs2506 SWALL:YEAR_ECOLI (SWALL:P76248) (119 aa) fasta scores: E(): 3.1e-30, 66.66% id in 105 aa, and to Salmonella typhi hypothetical protein Sty1850 SWALL:Q8Z6D6 (EMBL:AL627271) (120 aa) fasta scores: E(): 5.8e-30, 65.71% id in 105 aa. | Conserved hypothetical protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions. | 0.454 |
| hcr | hmpX | ECA2663 | ECA3251 | Similar to Escherichia coli NADH oxidoreductase Hcr or b0872 SWALL:HCR_ECOLI (SWALL:P75824) (322 aa) fasta scores: E(): 1.3e-46, 61.14% id in 332 aa. | Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | 0.657 |
| hcr | norV | ECA2663 | ECA0902 | Similar to Escherichia coli NADH oxidoreductase Hcr or b0872 SWALL:HCR_ECOLI (SWALL:P75824) (322 aa) fasta scores: E(): 1.3e-46, 61.14% id in 332 aa. | Anaerobic nitric oxide reductase flavorubredoxin; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family. | 0.476 |
| hcr | nsrR | ECA2663 | ECA3623 | Similar to Escherichia coli NADH oxidoreductase Hcr or b0872 SWALL:HCR_ECOLI (SWALL:P75824) (322 aa) fasta scores: E(): 1.3e-46, 61.14% id in 332 aa. | Conserved hypothetical protein; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. | 0.627 |
| hcr | ytfE | ECA2663 | ECA3606 | Similar to Escherichia coli NADH oxidoreductase Hcr or b0872 SWALL:HCR_ECOLI (SWALL:P75824) (322 aa) fasta scores: E(): 1.3e-46, 61.14% id in 332 aa. | Conserved hypothetical protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions. | 0.671 |
| hmpX | ECA1474 | ECA3251 | ECA1474 | Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein year or b1797 or z2839 or ecs2506 SWALL:YEAR_ECOLI (SWALL:P76248) (119 aa) fasta scores: E(): 3.1e-30, 66.66% id in 105 aa, and to Salmonella typhi hypothetical protein Sty1850 SWALL:Q8Z6D6 (EMBL:AL627271) (120 aa) fasta scores: E(): 5.8e-30, 65.71% id in 105 aa. | 0.657 |
| hmpX | hcr | ECA3251 | ECA2663 | Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | Similar to Escherichia coli NADH oxidoreductase Hcr or b0872 SWALL:HCR_ECOLI (SWALL:P75824) (322 aa) fasta scores: E(): 1.3e-46, 61.14% id in 332 aa. | 0.657 |
| hmpX | narG | ECA3251 | ECA2031 | Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | Similar to Escherichia coli respiratory nitrate reductase 1 alpha chain NarG or NarC or BisD or b1224 SWALL:NARG_ECOLI (SWALL:P09152) (1246 aa) fasta scores: E(): 0, 83.77% id in 1245 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.572 |
| hmpX | norV | ECA3251 | ECA0902 | Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | Anaerobic nitric oxide reductase flavorubredoxin; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family. | 0.803 |
| hmpX | nsrR | ECA3251 | ECA3623 | Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | Conserved hypothetical protein; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. | 0.716 |
| hmpX | tehB | ECA3251 | ECA0900 | Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | Similar to Escherichia coli tellurite resistance protein TehB or b1430 SWALL:TEHB_ECOLI (SWALL:P25397) (197 aa) fasta scores: E(): 3.4e-41, 60.73% id in 191 aa, and to Yersinia pestis tehb protein TehB or ypo1949 or y2361 SWALL:Q9ZC59 (EMBL:AL031866) (295 aa) fasta scores: E(): 3.3e-81, 70.21% id in 282 aa. | 0.657 |
| hmpX | ytfE | ECA3251 | ECA3606 | Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | Conserved hypothetical protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions. | 0.958 |
| ipdC | ytfE | ECA3605 | ECA3606 | Similar to Enterobacter cloacae indole-3-pyruvate decarboxylase IpdC SWALL:DCIP_ENTCL (SWALL:P23234) (552 aa) fasta scores: E(): 1.6e-115, 55.39% id in 556 aa, and to Salmonella typhimurium putative indole-3-pyruvate decarboxylase Ipd or stm2405 SWALL:Q93IM7 (EMBL:AJ401270) (550 aa) fasta scores: E(): 6.1e-118, 55.27% id in 559 aa. | Conserved hypothetical protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions. | 0.522 |
| narG | hmpX | ECA2031 | ECA3251 | Similar to Escherichia coli respiratory nitrate reductase 1 alpha chain NarG or NarC or BisD or b1224 SWALL:NARG_ECOLI (SWALL:P09152) (1246 aa) fasta scores: E(): 0, 83.77% id in 1245 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | 0.572 |
| narG | narJ | ECA2031 | ECA2033 | Similar to Escherichia coli respiratory nitrate reductase 1 alpha chain NarG or NarC or BisD or b1224 SWALL:NARG_ECOLI (SWALL:P09152) (1246 aa) fasta scores: E(): 0, 83.77% id in 1245 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Similar to Escherichia coli, and Escherichia coli O157:H7 respiratory nitrate reductase 1 delta chain NarJ or b1226 or z2003 or ecs1731 SWALL:NARJ_ECOLI (SWALL:P11351) (236 aa) fasta scores: E(): 8.1e-56, 62.18% id in 238 aa. | 0.998 |
| narG | ytfE | ECA2031 | ECA3606 | Similar to Escherichia coli respiratory nitrate reductase 1 alpha chain NarG or NarC or BisD or b1224 SWALL:NARG_ECOLI (SWALL:P09152) (1246 aa) fasta scores: E(): 0, 83.77% id in 1245 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Conserved hypothetical protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions. | 0.432 |
| narJ | narG | ECA2033 | ECA2031 | Similar to Escherichia coli, and Escherichia coli O157:H7 respiratory nitrate reductase 1 delta chain NarJ or b1226 or z2003 or ecs1731 SWALL:NARJ_ECOLI (SWALL:P11351) (236 aa) fasta scores: E(): 8.1e-56, 62.18% id in 238 aa. | Similar to Escherichia coli respiratory nitrate reductase 1 alpha chain NarG or NarC or BisD or b1224 SWALL:NARG_ECOLI (SWALL:P09152) (1246 aa) fasta scores: E(): 0, 83.77% id in 1245 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.998 |
| narJ | ytfE | ECA2033 | ECA3606 | Similar to Escherichia coli, and Escherichia coli O157:H7 respiratory nitrate reductase 1 delta chain NarJ or b1226 or z2003 or ecs1731 SWALL:NARJ_ECOLI (SWALL:P11351) (236 aa) fasta scores: E(): 8.1e-56, 62.18% id in 238 aa. | Conserved hypothetical protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions. | 0.473 |