STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3626Putative type II/IV secretion system protein; Similar to Escherichia coli hypothetical protein yggr or b2950 SWALL:YGGR_ECOLI (SWALL:P52052) (326 aa) fasta scores: E(): 4e-63, 60.67% id in 328 aa, and to Yersinia pestis hypothetical protein Ypo0940 SWALL:Q8ZHF9 (EMBL:AJ414145) (358 aa) fasta scores: E(): 1.4e-65, 60.92% id in 325 aa. (338 aa)    
Predicted Functional Partners:
outO
Type 4 prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
   
 0.860
hofC
Similar to Escherichia coli protein transport protein HofC or HopC or b0106 SWALL:HOFC_ECOLI (SWALL:P36646) (400 aa) fasta scores: E(): 5.6e-55, 40.15% id in 401 aa.
 
  
 0.817
outF
Similar to Erwinia carotovora general secretion pathway protein F OutF SWALL:GSPF_ERWCA (SWALL:P31705) (408 aa) fasta scores: E(): 7.6e-150, 96.56% id in 408 aa, and to Erwinia chrysanthemi general secretion pathway protein F OutF SWALL:GSPF_ERWCH (SWALL:P31704) (404 aa) fasta scores: E(): 1.2e-116, 77.39% id in 407 aa.
 
  
 0.816
hofQ
Putative type II secretion system protein; Similar to Escherichia coli protein transport protein HofQ precursor HofQ or HopQ or b3391 SWALL:HOFQ_ECOLI (SWALL:P34749) (412 aa) fasta scores: E(): 3.1e-71, 52.3% id in 390 aa, and to Yersinia pestis putative membrane transport protein ypo0150 or hofq or y3932 SWALL:Q8ZJF8 (EMBL:AJ414141) (374 aa) fasta scores: E(): 3.9e-84, 62.89% id in 380 aa.
 
   
 0.730
ECA3627
Putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
       0.600
ECA2558
Similar to Yersinia pestis putative membrane protein ypo1394 or y2778 SWALL:Q8ZGB0 (EMBL:AJ414148) (763 aa) fasta scores: E(): 7.2e-161, 50.19% id in 763 aa, and to Salmonella typhi putative competence-related protein sty0984 SWALL:Q8Z802 (EMBL:AL627268) (754 aa) fasta scores: E(): 7.2e-126, 42.52% id in 762 aa.
 
   
 0.568
outG
Similar to Erwinia carotovora general secretion pathway protein G precursor OutG SWALL:GSPG_ERWCA (SWALL:P31586) (156 aa) fasta scores: E(): 2.3e-51, 97.88% id in 142 aa, and to Erwinia chrysanthemi general secretion pathway protein G precursor OutG SWALL:GSPG_ERWCH (SWALL:P31585) (153 aa) fasta scores: E(): 1.9e-42, 85.07% id in 134 aa.
 
  
 0.556
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
  
 0.505
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
     
 0.479
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.477
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.