STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3629Similar to Yersinia pestis putative membrane protein ypo0943 or y3329 SWALL:Q8ZHF6 (EMBL:AJ414145) (184 aa) fasta scores: E(): 5.8e-58, 78.26% id in 184 aa, and to Vibrio cholerae hypothetical protein Vc0459 SWALL:Q9KUQ6 (EMBL:AE004132) (185 aa) fasta scores: E(): 2.3e-42, 56.21% id in 185 aa. (184 aa)    
Predicted Functional Partners:
ECA3630
Similar to Salmonella typhi hypothetical upf0235 protein yggu or sty3255 or t3014 SWALL:AAO70566 (EMBL:AL627277) (96 aa) fasta scores: E(): 1.1e-27, 78.12% id in 96 aa, and to Escherichia coli hypothetical upf0235 protein yggu or b2953 SWALL:YGGU_ECOLI (SWALL:P52060) (96 aa) fasta scores: E(): 2.6e-26, 76.84% id in 95 aa.
  
  
 0.838
ECA3631
Ham1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
    0.765
ECA3632
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.757
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
  
    0.746
ECA3627
Putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
  
  
 0.725
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.624
smpA
Putative outer membrane lipopotein (small protein A); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.574
ECA3341
Similar to Yersinia pestis hypothetical protein ypo1080 or y3096 SWALL:AAM86646 (EMBL:AJ414146) (239 aa) fasta scores: E(): 6.6e-62, 61.86% id in 236 aa, and to Salmonella typhimurium putative sam-dependent methyltransferase yafs or stm0262 SWALL:Q8ZRM1 (EMBL:AE008707) (240 aa) fasta scores: E(): 6.6e-60, 59.07% id in 237 aa.
 
     0.558
ECA4047
Putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
  
  
 0.536
rnfH
Conserved hypothetical protein; Similar to Escherichia coli O6 protein YfjF SWALL:AAN81590 (EMBL:AE016764) (102 aa) fasta scores: E(): 1.8e-23, 75% id in 92 aa, and to Escherichia coli protein YfjF SWALL:YFJF_ECOLI (SWALL:P52119) (96 aa) fasta scores: E(): 4.4e-23, 75% id in 92 aa; Belongs to the UPF0125 (RnfH) family.
  
     0.535
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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