STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3633Similar to Salmonella typhi hypothetical protein Sty3093 SWALL:Q8Z448 (EMBL:AL627276) (118 aa) fasta scores: E(): 4.3e-20, 75.94% id in 79 aa, and to Vibrio cholerae hypothetical protein Vca0360.1 SWALL:YV6A_VIBCH (SWALL:P58093) (80 aa) fasta scores: E(): 1.5e-05, 42.85% id in 77 aa. (87 aa)    
Predicted Functional Partners:
nadR
Similar to Salmonella typhimurium transcriptional regulator NadR SWALL:NADR_SALTY (SWALL:P24518) (410 aa) fasta scores: E(): 1.1e-140, 85.5% id in 407 aa, and to Escherichia coli transcriptional regulator NadR or NadI or b4390 SWALL:NADR_ECOLI (SWALL:P27278) (410 aa) fasta scores: E(): 2.2e-139, 83.9% id in 410 aa.
   
    0.846
ECA1466
Conserved hypothetical protein; Similar to Enterobacter aerogenes KluB SWALL:Q93KC5 (EMBL:U67194) (104 aa) fasta scores: E(): 1.4e-21, 58.41% id in 101 aa, and to Pseudomonas sp. hypothetical 11.6 kDa protein orf1 SWALL:Q937D2 (EMBL:U66917) (104 aa) fasta scores: E(): 8.5e-22, 59.4% id in 101 aa.
  
 
 0.753
ECA2758
Similar to Rhizobium sp. hypothetical 11.0 kDa protein Y4kP SWALL:Y4KP_RHISN (SWALL:P55534) (96 aa) fasta scores: E(): 4.6e-10, 43.82% id in 89 aa, and to Agrobacterium tumefaciens hypothetical protein atu1782 or agr_c_3278 SWALL:Q8UEH5 (EMBL:AE009134) (96 aa) fasta scores: E(): 4.5e-09, 42.22% id in 90 aa.
 
 
 0.657
ECA0409
Putative plasmid-related protein; Similar to Escherichia coli O157:H7 plasmid po157 DNA, complete sequence l7011 SWALL:O82928 (EMBL:AB011549) (91 aa) fasta scores: E(): 9.3e-12, 42.85% id in 91 aa, and to Shigella sonnei YacB protein yacB SWALL:Q9Z4G4 (EMBL:AB021078) (93 aa) fasta scores: E(): 0.63, 30% id in 90 aa.
  
 
 0.581
cobB
Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily.
   
    0.485
ECA3631
Ham1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.430
ECA3632
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.430
ECA3629
Similar to Yersinia pestis putative membrane protein ypo0943 or y3329 SWALL:Q8ZHF6 (EMBL:AJ414145) (184 aa) fasta scores: E(): 5.8e-58, 78.26% id in 184 aa, and to Vibrio cholerae hypothetical protein Vc0459 SWALL:Q9KUQ6 (EMBL:AE004132) (185 aa) fasta scores: E(): 2.3e-42, 56.21% id in 185 aa.
       0.407
ECA3630
Similar to Salmonella typhi hypothetical upf0235 protein yggu or sty3255 or t3014 SWALL:AAO70566 (EMBL:AL627277) (96 aa) fasta scores: E(): 1.1e-27, 78.12% id in 96 aa, and to Escherichia coli hypothetical upf0235 protein yggu or b2953 SWALL:YGGU_ECOLI (SWALL:P52060) (96 aa) fasta scores: E(): 2.6e-26, 76.84% id in 95 aa.
       0.407
ECA0587
Conserved hypothetical protein; Similar to Yersinia pestis putative DNA-binding prophage protein ypo1092 SWALL:Q8ZH21 (EMBL:AJ414146) (298 aa) fasta scores: E(): 4.4e-48, 48.79% id in 291 aa, and to Salmonella typhi hypothetical protein sty4586 SWALL:Q8Z1I0 (EMBL:AL627282) (306 aa) fasta scores: E(): 3e-46, 46.57% id in 292 aa, and to Salmonella typhimurium putative integrase stm2760 SWALL:Q8ZMP4 (EMBL:AE008825) (291 aa) fasta scores: E(): 9.7e-46, 46.07% id in 293 aa.
  
     0.405
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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