STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa)    
Predicted Functional Partners:
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
 0.989
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
     
 0.955
lysC
Similar to Escherichia coli lysine-sensitive aspartokinase III LysC or Apk or b4024 SWALL:AK3_ECOLI (SWALL:P08660) (449 aa) fasta scores: E(): 9.4e-136, 80.89% id in 445 aa; Belongs to the aspartokinase family.
 
 0.947
ECA1293
Similar to Yersinia pestis putative aspartate/glutamate racemase ypo2758 SWALL:Q8ZD34 (EMBL:AJ414153) (231 aa) fasta scores: E(): 2.5e-58, 67.54% id in 228 aa, and to Salmonella typhi hypothetical protein Sty3159 SWALL:Q8Z402 (EMBL:AL627277) (235 aa) fasta scores: E(): 1.6e-49, 55.89% id in 229 aa.
    
  0.944
ECA4114
Similar to Selenomonas ruminantium lysine/ornithine decarboxylase Ldc SWALL:DCLO_SELRU (SWALL:O50657) (393 aa) fasta scores: E(): 4.2e-06, 26.53% id in 245 aa, and to Rhizobium fredii Y4yA SWALL:Q9EUG5 (EMBL:AF229441) (450 aa) fasta scores: E(): 6.6e-73, 49.08% id in 438 aa.
  
  
 
0.896
argG
Argininosuccinate synthase; Similar to Escherichia coli, and Escherichia coli O6 argininosuccinate synthase ArgG or b3172 or c3929 SWALL:ASSY_ECOLI (SWALL:P22767) (446 aa) fasta scores: E(): 1.2e-162, 91.89% id in 444 aa; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
 
 
 0.824
thrA
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase I [includes: aspartokinase I; homoserine dehydrogenase I] thra or thra1 or thra2 or b0002 SWALL:AK1H_ECOLI (SWALL:P00561) (820 aa) fasta scores: E(): 0, 82.41% id in 819 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
 0.823
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 0.797
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
  
 0.720
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
   
 
 0.686
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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