STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tyrBSimilar to Escherichia coli aromatic-amino-acid aminotransferase tyrb or b4054 SWALL:TYRB_ECOLI (SWALL:P04693) (397 aa) fasta scores: E(): 1.9e-115, 74.24% id in 396 aa. (397 aa)    
Predicted Functional Partners:
pheA
Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri P-protein [includes: chorismate mutase and prephenate dehydratase] PheA or b2599 or z3891 or ecs3462 or sf2659 SWALL:PHEA_ECOLI (SWALL:P07022) (386 aa) fasta scores: E(): 1e-115, 76.17% id in 382 aa.
    
 0.946
tyrA
Similar to Escherichia coli T-protein [includes: chorismate mutase and prephenate dehydrogenase] TyrA or b2600 SWALL:TYRA_ECOLI (SWALL:P07023) (373 aa) fasta scores: E(): 1.6e-123, 87.13% id in 373 aa.
    
 0.945
mmuM
Similar to Escherichia coli homocysteine S-methyltransferase MmuM or b0261 SWALL:MMUM_ECOLI (SWALL:Q47690) (310 aa) fasta scores: E(): 2e-82, 68.85% id in 305 aa.
     
 0.944
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.917
aatA
Similar to Rhizobium meliloti aspartate aminotransferase A AatA or r02325 or smc01578 SWALL:AATA_RHIME (SWALL:Q02635) (400 aa) fasta scores: E(): 5.9e-80, 50.62% id in 399 aa, and to Agrobacterium tumefaciens aspartate aminotransferase A AatA or atu4278 or agr_l_1171 SWALL:Q8U821 (EMBL:AE009356) (412 aa) fasta scores: E(): 7.9e-115, 72.04% id in 397 aa.
   
 0.913
ECA2250
Putative aminotransferase; Similar to Xanthomonas campestris histidinol-phosphate aminotransferase hisc or xcc3275 SWALL:Q8P5R1 (EMBL:AE012444) (399 aa) fasta scores: E(): 2.9e-27, 31.33% id in 367 aa, and to Pseudomonas fluorescens putative aminotransferase qbsB SWALL:AAL65284 (EMBL:AY072690) (363 aa) fasta scores: E(): 1.1e-26, 32.2% id in 354 aa.
   
 
 0.912
hisC
Similar to Escherichia coli histidinol-phosphate aminotransferase HisC or b2021 SWALL:HIS8_ECOLI (SWALL:P06986) (356 aa) fasta scores: E(): 1e-103, 75.07% id in 349 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
   
 
 0.912
ECA1449
Putative chorismate mutase; Similar to Erwinia herbicola monofunctional chorismate mutase precursor AroQ SWALL:CHMU_ERWHE (SWALL:P42517) (181 aa) fasta scores: E(): 1.2e-18, 38.88% id in 180 aa, and to Yersinia pestis putative chorismate mutase ypo1353 or y2828 SWALL:Q8ZGE8 (EMBL:AJ414147) (186 aa) fasta scores: E(): 5.3e-17, 34.83% id in 178 aa.
    
 0.911
mtnD1
Probable oxidase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
     
 0.908
mtnD2
VgrG protein (pseudogene); Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
     
 0.908
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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