STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tyrBSimilar to Escherichia coli aromatic-amino-acid aminotransferase tyrb or b4054 SWALL:TYRB_ECOLI (SWALL:P04693) (397 aa) fasta scores: E(): 1.9e-115, 74.24% id in 396 aa. (397 aa)    
Predicted Functional Partners:
pheA
Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri P-protein [includes: chorismate mutase and prephenate dehydratase] PheA or b2599 or z3891 or ecs3462 or sf2659 SWALL:PHEA_ECOLI (SWALL:P07022) (386 aa) fasta scores: E(): 1e-115, 76.17% id in 382 aa.
    
 0.983
tyrA
Similar to Escherichia coli T-protein [includes: chorismate mutase and prephenate dehydrogenase] TyrA or b2600 SWALL:TYRA_ECOLI (SWALL:P07023) (373 aa) fasta scores: E(): 1.6e-123, 87.13% id in 373 aa.
    
 0.981
mmuM
Similar to Escherichia coli homocysteine S-methyltransferase MmuM or b0261 SWALL:MMUM_ECOLI (SWALL:Q47690) (310 aa) fasta scores: E(): 2e-82, 68.85% id in 305 aa.
     
 0.969
ECA2250
Putative aminotransferase; Similar to Xanthomonas campestris histidinol-phosphate aminotransferase hisc or xcc3275 SWALL:Q8P5R1 (EMBL:AE012444) (399 aa) fasta scores: E(): 2.9e-27, 31.33% id in 367 aa, and to Pseudomonas fluorescens putative aminotransferase qbsB SWALL:AAL65284 (EMBL:AY072690) (363 aa) fasta scores: E(): 1.1e-26, 32.2% id in 354 aa.
   
 
 0.954
hisC
Similar to Escherichia coli histidinol-phosphate aminotransferase HisC or b2021 SWALL:HIS8_ECOLI (SWALL:P06986) (356 aa) fasta scores: E(): 1e-103, 75.07% id in 349 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
   
 
 0.954
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
    
 0.952
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 
 0.949
ECA1449
Putative chorismate mutase; Similar to Erwinia herbicola monofunctional chorismate mutase precursor AroQ SWALL:CHMU_ERWHE (SWALL:P42517) (181 aa) fasta scores: E(): 1.2e-18, 38.88% id in 180 aa, and to Yersinia pestis putative chorismate mutase ypo1353 or y2828 SWALL:Q8ZGE8 (EMBL:AJ414147) (186 aa) fasta scores: E(): 5.3e-17, 34.83% id in 178 aa.
    
 0.949
mtnD1
Probable oxidase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
     
 0.949
mtnD2
VgrG protein (pseudogene); Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
     
 0.949
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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