Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ECA3744GntR-family transcriptional regulator; Similar to Escherichia coli O157:H7 z3973 protein z3973 or ecs3534 SWALL:Q8X922 (EMBL:AE005496) (444 aa) fasta scores: E(): 1.8e-78, 47.91% id in 455 aa, and to Salmonella typhimurium putative regulatory protein, GntR family stm2803 SWALL:Q8ZML3 (EMBL:AE008828) (444 aa) fasta scores: E(): 5.4e-76, 47.91% id in 455 aa. (472 aa)    
Predicted Functional Partners:
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
   
 
  0.821
ECA3743
Similar to Bacillus halodurans hypothetical protein Bh1582 bh1582 SWALL:Q9KCI9 (EMBL:AP001512) (143 aa) fasta scores: E(): 7.2e-05, 32.97% id in 94 aa, and to Oceanobacillus iheyensis hypothetical conserved protein ob0311 SWALL:BAC12267 (EMBL:AP004594) (140 aa) fasta scores: E(): 0.00065, 27.95% id in 93 aa.
       0.556
ECA3693
Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
     0.505
ECA2655
Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
     0.454
gcvP
Putative glycine cleavage system P protein (glycine dehydrogenase [decarboxylating]); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.452
ECA1350
Similar to Yersinia pestis hypothetical protein ypo2697 or y1272 SWALL:YQ97_YERPE (SWALL:Q8ZD91) (247 aa) fasta scores: E(): 1.6e-77, 76.92% id in 247 aa, and to Salmonella typhimurium, and Salmonella typhi hypothetical protein ybgi or stm0711 or sty0751 SWALL:YBGI_SALTY (SWALL:Q8XFW7) (247 aa) fasta scores: E(): 1.1e-71, 72.06% id in 247 aa.
   
    0.414
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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