Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ECA3759DeoR-family transcriptional regulator; Similar to Salmonella typhimurium, and Salmonella typhi putative transcriptional regulator stm0164 or sty0186 SWALL:Q8XG73 (EMBL:AE008701) (255 aa) fasta scores: E(): 6.1e-68, 72.61% id in 252 aa, and to Escherichia coli O6 putative transcriptional regulator c0765 SWALL:AAN79238 (EMBL:AE016757) (253 aa) fasta scores: E(): 4.6e-67, 73.96% id in 242 aa. (271 aa)    
Predicted Functional Partners:
fruK
1-phosphofructokinase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri 1-phosphofructokinase FruK or Fpk or b2168 or c2703 or z3426 or ecs3060 or sf2253 SWALL:K1PF_ECOLI (SWALL:P23539) (312 aa) fasta scores: E(): 7.8e-108, 90.7% id in 312 aa; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.699
fruA
Similar to Escherichia coli pts system, fructose-specific IIbc component FruA or PtsF or b2167 SWALL:PTFB_ECOLI (SWALL:P20966) (563 aa) fasta scores: E(): 1.4e-146, 75.13% id in 567 aa.
 
  
 0.681
dtnK
Conserved hypothetical protein; Catalyzes the ATP-dependent phosphorylation of D-threonate to D-threonate 4-phosphate. Can also phosphorylate 4-hydroxy-L-threonine, with lower efficiency.
 
     0.620
pdxA2
PdxA-like protein; Catalyzes the NAD-dependent oxidation and subsequent decarboxylation of D-threonate 4-phosphate to produce dihydroxyacetone phosphate (DHAP). Can also use 4-hydroxy-L-threonine 4-phosphate as substrate.
       0.494
ECA3519
Putative acyl-CoA synthetase; Similar to Yersinia pestis putative acetyltransferase ypo3272 SWALL:Q8ZBW2 (EMBL:AJ414156) (880 aa) fasta scores: E(): 0, 79.56% id in 881 aa, and to Escherichia coli hypothetical protein yfiq or b2584 SWALL:YFIQ_ECOLI (SWALL:P76594) (886 aa) fasta scores: E(): 0, 76.84% id in 881 aa.
    
   0.420
glpA
Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri anaerobic glycerol-3-phosphate dehydrogenase subunit A GlpA or b2241 or z3499 or ecs3126 or sf2323 SWALL:GLPA_ECOLI (SWALL:P13032) (542 aa) fasta scores: E(): 1.1e-153, 72.34% id in 546 aa; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.418
ECA0341
PTS system, IIb component; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri PTS system, fructose-like-2 IIb component 1 frwb or b3950 or c4908 or z5506 or ecs4879 or sf4027 SWALL:PTWB_ECOLI (SWALL:P32673) (106 aa) fasta scores: E(): 8.5e-14, 50% id in 100 aa, and to Escherichia coli O6 pts system, fructose-like-2 IIb component 1 c4486 SWALL:AAN82922 (EMBL:AE016769) (104 aa) fasta scores: E(): 2.1e-27, 80.19% id in 101 aa.
 
  
 0.401
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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