STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
pdxA2PdxA-like protein; Catalyzes the NAD-dependent oxidation and subsequent decarboxylation of D-threonate 4-phosphate to produce dihydroxyacetone phosphate (DHAP). Can also use 4-hydroxy-L-threonine 4-phosphate as substrate. (326 aa)    
Predicted Functional Partners:
dtnK
Conserved hypothetical protein; Catalyzes the ATP-dependent phosphorylation of D-threonate to D-threonate 4-phosphate. Can also phosphorylate 4-hydroxy-L-threonine, with lower efficiency.
     0.953
pdxJ
Pyridoxal phosphate biosynthetic protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
 
  
 0.801
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
     
 0.724
ECA3762
Similar to Escherichia coli O6 putative alcohol dehydrogenase c0762 SWALL:Q8FJW8 (EMBL:AE016757) (385 aa) fasta scores: E(): 1.1e-83, 61.96% id in 376 aa, and to Agrobacterium tumefaciens AttL SWALL:Q8VPD6 (EMBL:AY052389) (399 aa) fasta scores: E(): 4.6e-36, 35.84% id in 371 aa.
 
     0.555
ECA3763
Similar to Bacillus subtilis dihydrodipicolinate synthase DapA SWALL:DAPA_BACSU (SWALL:Q04796) (290 aa) fasta scores: E(): 2.9e-26, 34.16% id in 281 aa, and to Escherichia coli O6 putative dihydrodipicolinate synthase c0761 SWALL:AAN79234 (EMBL:AE016757) (295 aa) fasta scores: E(): 1.9e-75, 67.91% id in 293 aa; Belongs to the DapA family.
 
  
 0.523
ECA3765
Similar to Escherichia coli O6 hypothetical protein c0759 SWALL:AAN79232 (EMBL:AE016757) (389 aa) fasta scores: E(): 1.2e-112, 70.18% id in 389 aa, and to Agrobacterium tumefaciens hypothetical protein atu5072 or agr_pat_102 SWALL:Q8UKM8 (EMBL:AE008932) (397 aa) fasta scores: E(): 2.4e-68, 47.13% id in 401 aa.
 
     0.514
ECA3759
DeoR-family transcriptional regulator; Similar to Salmonella typhimurium, and Salmonella typhi putative transcriptional regulator stm0164 or sty0186 SWALL:Q8XG73 (EMBL:AE008701) (255 aa) fasta scores: E(): 6.1e-68, 72.61% id in 252 aa, and to Escherichia coli O6 putative transcriptional regulator c0765 SWALL:AAN79238 (EMBL:AE016757) (253 aa) fasta scores: E(): 4.6e-67, 73.96% id in 242 aa.
       0.494
kdgT
2-keto-3-deoxygluconate permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system. Belongs to the KdgT transporter family.
 
     0.472
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.466
otnK
Conserved hypothetical protein; Catalyzes the ATP-dependent phosphorylation of 3-oxo- tetronate to 3-oxo-tetronate 4-phosphate.
 
     0.424
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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