STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3763Similar to Bacillus subtilis dihydrodipicolinate synthase DapA SWALL:DAPA_BACSU (SWALL:Q04796) (290 aa) fasta scores: E(): 2.9e-26, 34.16% id in 281 aa, and to Escherichia coli O6 putative dihydrodipicolinate synthase c0761 SWALL:AAN79234 (EMBL:AE016757) (295 aa) fasta scores: E(): 1.9e-75, 67.91% id in 293 aa; Belongs to the DapA family. (294 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
 
 0.994
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 
 0.979
thrA
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase I [includes: aspartokinase I; homoserine dehydrogenase I] thra or thra1 or thra2 or b0002 SWALL:AK1H_ECOLI (SWALL:P00561) (820 aa) fasta scores: E(): 0, 82.41% id in 819 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.963
metL
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase II MetL or MetM or b3940 SWALL:AK2H_ECOLI (SWALL:P00562) (809 aa) fasta scores: E(): 0, 83.12% id in 800 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.963
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
  
 
0.957
ECA4425
Putative dihydrodipicolinate synthetase; Similar to Bradyrhizobium japonicum Bll7272 protein bll7272 SWALL:BAC52537 (EMBL:AP005961) (291 aa) fasta scores: E(): 3.2e-70, 65.97% id in 288 aa, and to Pseudomonas aeruginosa probable dihydrodipicolinate synthetase pa0223 SWALL:Q9I6R5 (EMBL:AE004460) (293 aa) fasta scores: E(): 8.8e-24, 32.29% id in 288 aa.
  
  
0.920
ECA3059
Similar to Shewanella violacea aspartate-semialdehyde dehydrogenase Asd SWALL:DHAS_SHEVI (SWALL:Q56734) (338 aa) fasta scores: E(): 1.3e-55, 45.1% id in 337 aa, and to Yersinia pestis putative aspartate-semialdehyde dehydrogenase Asd or ypo2765 or usg or y1598 SWALL:Q8ZD28 (EMBL:AJ414153) (336 aa) fasta scores: E(): 2.8e-104, 80.59% id in 335 aa.
 
 
 0.808
ECA3765
Similar to Escherichia coli O6 hypothetical protein c0759 SWALL:AAN79232 (EMBL:AE016757) (389 aa) fasta scores: E(): 1.2e-112, 70.18% id in 389 aa, and to Agrobacterium tumefaciens hypothetical protein atu5072 or agr_pat_102 SWALL:Q8UKM8 (EMBL:AE008932) (397 aa) fasta scores: E(): 2.4e-68, 47.13% id in 401 aa.
 
   
 0.784
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 
 0.769
ECA3764
Similar to Pseudomonas aeruginosa probable sodium:solute symporter pa0287 SWALL:Q9I6K3 (EMBL:AE004466) (461 aa) fasta scores: E(): 4.1e-21, 23.02% id in 456 aa, and to Vibrio vulnificus na+/proline symporter vv20592 SWALL:AAO07538 (EMBL:AE016810) (492 aa) fasta scores: E(): 8.5e-19, 25.05% id in 455 aa; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.724
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.