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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhRPyruvate dehydrogenase complex repressor; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 pyruvate dehydrogenase complex repressor PdhR or GenA or AceC or b0113 or c0140 or z0123 or ecs0117 SWALL:PDHR_ECOLI (SWALL:P06957) (254 aa) fasta scores: E(): 2.9e-77, 82.28% id in 254 aa. (254 aa)    
Predicted Functional Partners:
ECA1921
L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.622
aceE
Pyruvate dehydrogenase e1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
  
 0.607
nadR
Similar to Salmonella typhimurium transcriptional regulator NadR SWALL:NADR_SALTY (SWALL:P24518) (410 aa) fasta scores: E(): 1.1e-140, 85.5% id in 407 aa, and to Escherichia coli transcriptional regulator NadR or NadI or b4390 SWALL:NADR_ECOLI (SWALL:P27278) (410 aa) fasta scores: E(): 2.2e-139, 83.9% id in 410 aa.
   
  
 0.540
ECA2115
Similar to Rhizobium meliloti putative GntR-family transcriptional regulator ra0971 or sma1759 SWALL:Q92YB3 (EMBL:AE007283) (226 aa) fasta scores: E(): 4.3e-29, 45.23% id in 210 aa, and to Brucella suis transcriptional regulator, putative bra1096 SWALL:AAN34260 (EMBL:AE014602) (237 aa) fasta scores: E(): 3e-22, 40.65% id in 214 aa.
  
  
 0.534
aceF
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
  
 0.531
lctD
L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
  
  
 0.495
fadR
Fatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism.
  
   
 0.464
ECA0921
GntR-family transcriptional regulator; Similar to Escherichia coli, and Escherichia coli O157:H7 hypothetical transcriptional regulator YdfH SWALL:YDFH_ECOLI (SWALL:P77577) (228 aa) fasta scores: E(): 2e-51, 60.88% id in 225 aa, and to Salmonella typhimurium, and Salmonella typhi putative regulatory protein, GntR-family stm1510 or sty1551 SWALL:Q8XFZ6 (EMBL:AE008766) (228 aa) fasta scores: E(): 2.3e-50, 60% id in 225 aa.
  
  
 0.462
syd
Putative SecY-interacting protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.
  
     0.443
nfi
Endonuclease V (pseudogene); 1 probable transmembrane helix predicted for ECA0236 by TMHMM2.0 at aa 102-124.
  
     0.421
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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