Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ampEPutative membrane-bound sensory transducer; Similar to Escherichia coli, and Shigella flexneri AmpE protein AmpE or b0111 or sf0108 SWALL:AMPE_ECOLI (SWALL:P13017) (284 aa) fasta scores: E(): 6.6e-77, 66.19% id in 284 aa. (284 aa)    
Predicted Functional Partners:
ampD
anhydro-N-acetylmuramyl-tripeptide amidase; Similar to Escherichia coli ampd protein AmpD or b0110 SWALL:AMPD_ECOLI (SWALL:P13016) (183 aa) fasta scores: E(): 1.2e-51, 67.21% id in 183 aa, and to Enterobacter cloacae AmpD protein AmpD SWALL:AMPD_ENTCL (SWALL:P82973) (187 aa) fasta scores: E(): 5.9e-53, 69.1% id in 178 aa.
  
  
 0.875
ECA2552
Similar to Yersinia pestis hypothetical protein Ypo1401 SWALL:Q8ZGA3 (EMBL:AJ414148) (297 aa) fasta scores: E(): 4.9e-98, 73.4% id in 297 aa, and to Salmonella typhimurium mukf protein stm0989 SWALL:Q8ZQB9 (EMBL:AE008742) (297 aa) fasta scores: E(): 2e-77, 58.78% id in 296 aa.
  
     0.767
ECA3661
Putative membrane protein; Similar to Yersinia pestis putative exported protein ypo0318 or y0575 SWALL:AAM84163 (EMBL:AJ414142) (72 aa) fasta scores: E(): 3.3e-15, 66.66% id in 69 aa, and to Salmonella typhimurium, and Salmonella typhi putative inner membrane protein yjbo or stm4244 or sty4440 SWALL:Q8XFK0 (EMBL:AE008898) (80 aa) fasta scores: E(): 9.7e-13, 53.84% id in 78 aa.
  
     0.754
ECA2253
Putative exported protein; Similar to Yersinia pseudotuberculosis hypothetical 14.2 kDa protein orf9 SWALL:Q93AP0 (EMBL:AF418982) (124 aa) fasta scores: E(): 8.4e-19, 45.52% id in 123 aa, and to Salmonella typhimurium, and Salmonella typhi putative periplasmic protein ynfb or stm1503 or sty1560 SWALL:Q8XEU2 (EMBL:AE008765) (113 aa) fasta scores: E(): 3.1e-18, 52.52% id in 99 aa; Belongs to the UPF0482 family.
  
     0.752
aaeX
Putative membrane protein; Similar to Serratia marcescens hypothetical 7.8 kDa protein yhcR SWALL:Q8RQS4 (EMBL:AB080601) (67 aa) fasta scores: E(): 3.5e-20, 80.64% id in 62 aa, and to Yersinia pestis putative membrane protein ypo3684 or y0179 SWALL:Q8ZAV0 (EMBL:AJ414158) (67 aa) fasta scores: E(): 5.7e-20, 76.56% id in 64 aa.
  
     0.751
mzrA
Putative exported protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
  
     0.741
ECA2388
Similar to Yersinia pestis putative membrane protein ypo1755 or y2554 SWALL:AAM86109 (EMBL:AJ414150) (153 aa) fasta scores: E(): 3e-41, 73.02% id in 152 aa, and to Escherichia coli, and Escherichia coli O6 hypothetical protein yobd or b1820 or c2227 SWALL:YOBD_ECOLI (SWALL:P76263) (152 aa) fasta scores: E(): 8.8e-33, 57.89% id in 152 aa.
  
     0.732
flk
Cell division protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.
  
     0.725
ECA1289
Similar to Yersinia pestis putative membrane protein ypo3055 SWALL:Q8ZCD6 (EMBL:AJ414155) (64 aa) fasta scores: E(): 1.4e-19, 73.84% id in 65 aa, and to Salmonella typhimurium, and Salmonella typhi putative inner membrane protein stm2484 or sty2722 SWALL:Q8XF02 (EMBL:AE008812) (66 aa) fasta scores: E(): 5.5e-17, 66.12% id in 62 aa.
  
     0.723
ECA1784
Conserved hypothetical protein; Similar to Salmonella typhimurium putative cytoplasmic protein ycep or stm1161 SWALL:Q8ZQ21 (EMBL:AE008750) (84 aa) fasta scores: E(): 1.1e-21, 67.85% id in 84 aa, and to Escherichia coli, and Escherichia coli O6 hypothetical protein ycep or b1060 or c1327 SWALL:YCEP_ECOLI (SWALL:P75927) (84 aa) fasta scores: E(): 1.1e-21, 67.85% id in 84 aa.
  
     0.722
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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