STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbpASimilar to Escherichia coli thiamine-binding periplasmic protein precursor TbpA or ThiB or b0068 SWALL:TBPA_ECOLI (SWALL:P31550) (327 aa) fasta scores: E(): 3.9e-102, 73.31% id in 326 aa. (354 aa)    
Predicted Functional Partners:
thiP
Similar to Escherichia coli thiamine transport system permease protein ThiP or b0067 SWALL:THIP_ECOLI (SWALL:P31549) (536 aa) fasta scores: E(): 1.3e-154, 75% id in 532 aa.
 
 
 0.994
thiQ
Thiamine transport ATP-binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
 
 
  0.978
ECA1027
Similar to Yersinia pestis hypothetical protein ypo1040 or y3141 SWALL:AAM86691 (EMBL:AJ414146) (129 aa) fasta scores: E(): 3.2e-38, 84.49% id in 129 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yaeh or b0163 or c0200 or z0175 or ecs0167 or sf0155 SWALL:AAN41817 (EMBL:D26562) (128 aa) fasta scores: E(): 8.4e-38, 85.82% id in 127 aa; Belongs to the UPF0325 family.
  
     0.476
fusA
Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
      
 0.475
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
      
 0.473
ECA3843
Similar to Burkholderia cepacia putative transcriptional regulator CeoR SWALL:Q8VL17 (EMBL:AY008288) (334 aa) fasta scores: E(): 1e-47, 45.27% id in 296 aa, and to Salmonella typhi putative transcriptional regulator sty1386 SWALL:Q8Z7A3 (EMBL:AL627270) (301 aa) fasta scores: E(): 1.3e-47, 45.36% id in 302 aa; Belongs to the LysR transcriptional regulatory family.
       0.425
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
   
  
 0.408
ECA1469
Similar to Brucella suis iron compound ABC transporter, permease protein, putative bra0699 SWALL:AAN33884 (EMBL:AE014565) (589 aa) fasta scores: E(): 1.3e-97, 51.53% id in 553 aa, and to Agrobacterium tumefaciens ABC transporter, membrane spanning protein fbpa3 or atu0408 or agr_c_717 SWALL:Q8UI90 (EMBL:AE009011) (558 aa) fasta scores: E(): 1.3e-95, 52.94% id in 527 aa.
  
  
 0.404
sfuB
Similar to Serratia marcescens iron(III)-transport system permease protein SfuB SWALL:SFUB_SERMA (SWALL:P21409) (527 aa) fasta scores: E(): 7.3e-141, 71.29% id in 526 aa, and to Yersinia pestis iron(III)-transport system permease protein SfuB or ypo2959 SWALL:Q8ZCM3 (EMBL:AJ414154) (528 aa) fasta scores: E(): 2.2e-139, 70.61% id in 524 aa.
  
  
 0.404
ECA3331
ABC transporter, permease protein; Similar to Vibrio cholerae iron vc0609 SWALL:Q9KUB4 (EMBL:AE004146) (541 aa) fasta scores: E(): 2.7e-75, 41.11% id in 540 aa, and to Pasteurella multocida fbpb fbpb or pm0050 SWALL:Q9CPI8 (EMBL:AE006038) (552 aa) fasta scores: E(): 6.1e-78, 41.3% id in 552 aa.
  
  
 0.404
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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