node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ECA2744 | hepA | ECA2744 | ECA3853 | Putative helicase; Similar to Yersinia pestis putative dead box helicase family protein ypo1265 or y2919 SWALL:AAM86469 (EMBL:AJ414147) (585 aa) fasta scores: E(): 6.6e-185, 80.3% id in 584 aa, and to Salmonella typhimurium, and Salmonella typhi putative ATP-dependent helicase yejh or stm2223 or sty2460 SWALL:Q8XGB8 (EMBL:AE008799) (586 aa) fasta scores: E(): 2.5e-180, 77.81% id in 586 aa. | RNA polymerase associated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.857 |
ECA2744 | polA | ECA2744 | ECA0021 | Putative helicase; Similar to Yersinia pestis putative dead box helicase family protein ypo1265 or y2919 SWALL:AAM86469 (EMBL:AJ414147) (585 aa) fasta scores: E(): 6.6e-185, 80.3% id in 584 aa, and to Salmonella typhimurium, and Salmonella typhi putative ATP-dependent helicase yejh or stm2223 or sty2460 SWALL:Q8XGB8 (EMBL:AE008799) (586 aa) fasta scores: E(): 2.5e-180, 77.81% id in 586 aa. | Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.678 |
ECA2744 | rpoA | ECA2744 | ECA4006 | Putative helicase; Similar to Yersinia pestis putative dead box helicase family protein ypo1265 or y2919 SWALL:AAM86469 (EMBL:AJ414147) (585 aa) fasta scores: E(): 6.6e-185, 80.3% id in 584 aa, and to Salmonella typhimurium, and Salmonella typhi putative ATP-dependent helicase yejh or stm2223 or sty2460 SWALL:Q8XGB8 (EMBL:AE008799) (586 aa) fasta scores: E(): 2.5e-180, 77.81% id in 586 aa. | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.900 |
ECA2744 | rpoB | ECA2744 | ECA0223 | Putative helicase; Similar to Yersinia pestis putative dead box helicase family protein ypo1265 or y2919 SWALL:AAM86469 (EMBL:AJ414147) (585 aa) fasta scores: E(): 6.6e-185, 80.3% id in 584 aa, and to Salmonella typhimurium, and Salmonella typhi putative ATP-dependent helicase yejh or stm2223 or sty2460 SWALL:Q8XGB8 (EMBL:AE008799) (586 aa) fasta scores: E(): 2.5e-180, 77.81% id in 586 aa. | DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.908 |
ECA2744 | rpoZ | ECA2744 | ECA0039 | Putative helicase; Similar to Yersinia pestis putative dead box helicase family protein ypo1265 or y2919 SWALL:AAM86469 (EMBL:AJ414147) (585 aa) fasta scores: E(): 6.6e-185, 80.3% id in 584 aa, and to Salmonella typhimurium, and Salmonella typhi putative ATP-dependent helicase yejh or stm2223 or sty2460 SWALL:Q8XGB8 (EMBL:AE008799) (586 aa) fasta scores: E(): 2.5e-180, 77.81% id in 586 aa. | DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.911 |
ECA2744 | xni | ECA2744 | ECA1018 | Putative helicase; Similar to Yersinia pestis putative dead box helicase family protein ypo1265 or y2919 SWALL:AAM86469 (EMBL:AJ414147) (585 aa) fasta scores: E(): 6.6e-185, 80.3% id in 584 aa, and to Salmonella typhimurium, and Salmonella typhi putative ATP-dependent helicase yejh or stm2223 or sty2460 SWALL:Q8XGB8 (EMBL:AE008799) (586 aa) fasta scores: E(): 2.5e-180, 77.81% id in 586 aa. | Exodeoxyribonuclease IX; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.615 |
dnaN | hepA | ECA4440 | ECA3853 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | RNA polymerase associated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.899 |
dnaN | polA | ECA4440 | ECA0021 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.989 |
dnaN | polB | ECA4440 | ECA3852 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | DNA polymerase II; Similar to Escherichia coli DNA polymerase II PolB or DinA or b0060 SWALL:DPO2_ECOLI (SWALL:P21189) (782 aa) fasta scores: E(): 0, 72.25% id in 782 aa. | 0.976 |
dnaN | recA | ECA4440 | ECA3369 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | RecA protein (recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.908 |
dnaN | rpoA | ECA4440 | ECA4006 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.754 |
dnaN | rpoB | ECA4440 | ECA0223 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.633 |
dnaN | rpoZ | ECA4440 | ECA0039 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.421 |
dnaN | xni | ECA4440 | ECA1018 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Exodeoxyribonuclease IX; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.947 |
hepA | ECA2744 | ECA3853 | ECA2744 | RNA polymerase associated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | Putative helicase; Similar to Yersinia pestis putative dead box helicase family protein ypo1265 or y2919 SWALL:AAM86469 (EMBL:AJ414147) (585 aa) fasta scores: E(): 6.6e-185, 80.3% id in 584 aa, and to Salmonella typhimurium, and Salmonella typhi putative ATP-dependent helicase yejh or stm2223 or sty2460 SWALL:Q8XGB8 (EMBL:AE008799) (586 aa) fasta scores: E(): 2.5e-180, 77.81% id in 586 aa. | 0.857 |
hepA | dnaN | ECA3853 | ECA4440 | RNA polymerase associated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.899 |
hepA | hsdR | ECA3853 | ECA3122 | RNA polymerase associated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | Similar to Escherichia coli type I restriction enzyme EcoEI R protein HsdR or Hsr SWALL:T1RE_ECOLI (SWALL:Q47281) (813 aa) fasta scores: E(): 0, 94.71% id in 813 aa, and to Pseudomonas putida type I restriction-modification system, R subunit hsdr or pp4740 SWALL:AAN70312 (EMBL:AE016791) (787 aa) fasta scores: E(): 3.5e-149, 61.76% id in 803 aa. | 0.802 |
hepA | polA | ECA3853 | ECA0021 | RNA polymerase associated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.911 |
hepA | polB | ECA3853 | ECA3852 | RNA polymerase associated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | DNA polymerase II; Similar to Escherichia coli DNA polymerase II PolB or DinA or b0060 SWALL:DPO2_ECOLI (SWALL:P21189) (782 aa) fasta scores: E(): 0, 72.25% id in 782 aa. | 0.795 |
hepA | recA | ECA3853 | ECA3369 | RNA polymerase associated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | RecA protein (recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.795 |